Fatty acids and insulin resistance: A perfect storm

Seung Hoi Koo; Marc Montminy

doi:10.1016/j.molcel.2006.02.001

Fatty acids and insulin resistance: A perfect storm

Seung Hoi Koo, Marc Montminy

Research output: Contribution to journal › Short survey › peer-review

16 Citations (Scopus)

Abstract

VLDL levels are elevated in type II diabetes, where they contribute to the risk of coronary heart disease. A study by Wolfrum and Stoffel (2006) shows that the forkhead protein Foxa2 stimulates hepatic VLDL production in concert with the coactivator PGC-1β and that insulin inhibits this process by inactivating Foxa2.

Original language	English
Pages (from-to)	449-450
Number of pages	2
Journal	Molecular Cell
Volume	21
Issue number	4
DOIs	https://doi.org/10.1016/j.molcel.2006.02.001
Publication status	Published - 2006 Feb 17
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.molcel.2006.02.001

Cite this

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title = "Fatty acids and insulin resistance: A perfect storm",

abstract = "VLDL levels are elevated in type II diabetes, where they contribute to the risk of coronary heart disease. A study by Wolfrum and Stoffel (2006) shows that the forkhead protein Foxa2 stimulates hepatic VLDL production in concert with the coactivator PGC-1β and that insulin inhibits this process by inactivating Foxa2.",

author = "Koo, {Seung Hoi} and Marc Montminy",

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doi = "10.1016/j.molcel.2006.02.001",

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journal = "Molecular Cell",

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T1 - Fatty acids and insulin resistance

T2 - A perfect storm

AU - Koo, Seung Hoi

AU - Montminy, Marc

PY - 2006/2/17

Y1 - 2006/2/17

N2 - VLDL levels are elevated in type II diabetes, where they contribute to the risk of coronary heart disease. A study by Wolfrum and Stoffel (2006) shows that the forkhead protein Foxa2 stimulates hepatic VLDL production in concert with the coactivator PGC-1β and that insulin inhibits this process by inactivating Foxa2.

AB - VLDL levels are elevated in type II diabetes, where they contribute to the risk of coronary heart disease. A study by Wolfrum and Stoffel (2006) shows that the forkhead protein Foxa2 stimulates hepatic VLDL production in concert with the coactivator PGC-1β and that insulin inhibits this process by inactivating Foxa2.

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U2 - 10.1016/j.molcel.2006.02.001

DO - 10.1016/j.molcel.2006.02.001

M3 - Short survey

C2 - 16483925

AN - SCOPUS:32444436362

SN - 1097-2765

VL - 21

SP - 449

EP - 450

JO - Molecular Cell

JF - Molecular Cell

IS - 4

ER -

Fatty acids and insulin resistance: A perfect storm

Abstract

ASJC Scopus subject areas

UN SDGs

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