Fatty acids and insulin resistance: A perfect storm

Seung Hoi Koo, Marc Montminy

Research output: Contribution to journalShort surveypeer-review

16 Citations (Scopus)


VLDL levels are elevated in type II diabetes, where they contribute to the risk of coronary heart disease. A study by Wolfrum and Stoffel (2006) shows that the forkhead protein Foxa2 stimulates hepatic VLDL production in concert with the coactivator PGC-1β and that insulin inhibits this process by inactivating Foxa2.

Original languageEnglish
Pages (from-to)449-450
Number of pages2
JournalMolecular Cell
Issue number4
Publication statusPublished - 2006 Feb 17
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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