Femto molar detection of a prostatespecific antigen (PSA) using a dynamic selfexciting nanomechanical cantilever

Jeong Hoon Lee, Kyo Seon Hwang, Ga Young Han, Ki Yong Choi, Dae Sung Yoon, Tae Song Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Methods are described to achieve the quantitative analysis up to femtomolar detection using nanomechanical cantilever. we fabricate a nanomechanical sensor that inherently detects the dynamic response variation of cantilever arrays. Here, the clinical discrimination of PSA Ag-Ab interaction up to femto molar level is accomplished by the resonant frequency shift.

Original languageEnglish
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
Subtitle of host publication9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages799-801
Number of pages3
ISBN (Print)0974361119, 9780974361116
Publication statusPublished - 2005
Externally publishedYes
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: 2005 Oct 92005 Oct 13

Publication series

NameMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume1

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Country/TerritoryUnited States
CityBoston, MA
Period05/10/905/10/13

Keywords

  • Cantilever
  • Dynamic mode
  • Nanomechanics
  • Protein detection

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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