Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Yong Jun Choi; Yae Jean Kim; Dongeun Yong; Jung Hyun Byun; Taek Soo Kim; Yun Sil Chang; Min Ji Choi; Seung Ah Byeon; Eun Jeong Won; Soo Hyun Kim; Myung Geun Shin; Jong Hee Shin

doi:10.3201/eid2409.180625

Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Yong Jun Choi
, Yae Jean Kim
, Dongeun Yong
, Jung Hyun Byun
, Taek Soo Kim
, Yun Sil Chang
, Min Ji Choi
, Seung Ah Byeon
, Eun Jeong Won
, Soo Hyun Kim
, Myung Geun Shin
, Jong Hee Shin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

75 Citations (Scopus)

Abstract

We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

Original language	English
Pages (from-to)	1768-1770
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	24
Issue number	9
DOIs	https://doi.org/10.3201/eid2409.180625
Publication status	Published - 2018 Sept
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2018, Centers for Disease Control and Prevention (CDC). All rights reserved.

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3201/eid2409.180625

Cite this

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title = "Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea",

abstract = "We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.",

author = "Choi, \{Yong Jun\} and Kim, \{Yae Jean\} and Dongeun Yong and Byun, \{Jung Hyun\} and Kim, \{Taek Soo\} and Chang, \{Yun Sil\} and Choi, \{Min Ji\} and Byeon, \{Seung Ah\} and Won, \{Eun Jeong\} and Kim, \{Soo Hyun\} and Shin, \{Myung Geun\} and Shin, \{Jong Hee\}",

year = "2018",

month = sep,

doi = "10.3201/eid2409.180625",

language = "English",

volume = "24",

pages = "1768--1770",

journal = "Emerging Infectious Diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

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}

TY - JOUR

T1 - Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

AU - Choi, Yong Jun

AU - Kim, Yae Jean

AU - Yong, Dongeun

AU - Byun, Jung Hyun

AU - Kim, Taek Soo

AU - Chang, Yun Sil

AU - Choi, Min Ji

AU - Byeon, Seung Ah

AU - Won, Eun Jeong

AU - Kim, Soo Hyun

AU - Shin, Myung Geun

AU - Shin, Jong Hee

PY - 2018/9

Y1 - 2018/9

N2 - We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

AB - We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

UR - https://www.scopus.com/pages/publications/85052192895

U2 - 10.3201/eid2409.180625

DO - 10.3201/eid2409.180625

M3 - Article

C2 - 30124412

AN - SCOPUS:85052192895

SN - 1080-6040

VL - 24

SP - 1768

EP - 1770

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 9

ER -

Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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