Abstract
A coumarin-based dithiane (1) was synthesized for the selective detection of Hg2+ with respect to dual chromo- and fluorogenic changing events in an aqueous solution by the mercury-promoted transformation of a dithiane group into an aldehyde functional unit. The Hg2+-selective response of the chemodosimeter was clearly observed in aqueous buffer as well as in human blood plasma medium.
Original language | English |
---|---|
Pages (from-to) | 5958-5961 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 50 |
Issue number | 43 |
DOIs | |
Publication status | Published - 2009 Oct 28 |
Keywords
- Chromogenic
- Coumarin
- Fluorogenic
- Mercury ion
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry