Fluorescent coumarinyldithiane as a selective chemodosimeter for mercury(II) ion in aqueous solution

Ja Hyung Kim; Hyun Jung Kim; Sang Hoon Kim; Jae Hong Lee; Jung Ho Do; Hae Jo Kim; Joung Hae Lee; Jong Seung Kim

doi:10.1016/j.tetlet.2009.08.045

Fluorescent coumarinyldithiane as a selective chemodosimeter for mercury(II) ion in aqueous solution

Ja Hyung Kim
, Hyun Jung Kim
, Sang Hoon Kim
, Jae Hong Lee
, Jung Ho Do
, Hae Jo Kim^*
, Joung Hae Lee
, Jong Seung Kim

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

A coumarin-based dithiane (1) was synthesized for the selective detection of Hg²⁺ with respect to dual chromo- and fluorogenic changing events in an aqueous solution by the mercury-promoted transformation of a dithiane group into an aldehyde functional unit. The Hg²⁺-selective response of the chemodosimeter was clearly observed in aqueous buffer as well as in human blood plasma medium.

Original language	English
Pages (from-to)	5958-5961
Number of pages	4
Journal	Tetrahedron Letters
Volume	50
Issue number	43
DOIs	https://doi.org/10.1016/j.tetlet.2009.08.045
Publication status	Published - 2009 Oct 28

Bibliographical note

Funding Information:
This work was supported by the Creative Research Initiative Program of the MEST, SRC (No. R11-2005-008-00000-0 ) and KRF ( KRF-2008-313-C00501 and KRF-2008-313-C00508 ).

Keywords

Chromogenic
Coumarin
Fluorogenic
Mercury ion

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2009.08.045

Cite this

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title = "Fluorescent coumarinyldithiane as a selective chemodosimeter for mercury(II) ion in aqueous solution",

abstract = "A coumarin-based dithiane (1) was synthesized for the selective detection of Hg2+ with respect to dual chromo- and fluorogenic changing events in an aqueous solution by the mercury-promoted transformation of a dithiane group into an aldehyde functional unit. The Hg2+-selective response of the chemodosimeter was clearly observed in aqueous buffer as well as in human blood plasma medium.",

keywords = "Chromogenic, Coumarin, Fluorogenic, Mercury ion",

author = "Kim, \{Ja Hyung\} and Kim, \{Hyun Jung\} and Kim, \{Sang Hoon\} and Lee, \{Jae Hong\} and Do, \{Jung Ho\} and Kim, \{Hae Jo\} and Lee, \{Joung Hae\} and Kim, \{Jong Seung\}",

note = "Funding Information: This work was supported by the Creative Research Initiative Program of the MEST, SRC (No. R11-2005-008-00000-0 ) and KRF ( KRF-2008-313-C00501 and KRF-2008-313-C00508 ). ",

year = "2009",

month = oct,

day = "28",

doi = "10.1016/j.tetlet.2009.08.045",

language = "English",

volume = "50",

pages = "5958--5961",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Fluorescent coumarinyldithiane as a selective chemodosimeter for mercury(II) ion in aqueous solution

AU - Kim, Ja Hyung

AU - Kim, Hyun Jung

AU - Kim, Sang Hoon

AU - Lee, Jae Hong

AU - Do, Jung Ho

AU - Kim, Hae Jo

AU - Lee, Joung Hae

AU - Kim, Jong Seung

N1 - Funding Information: This work was supported by the Creative Research Initiative Program of the MEST, SRC (No. R11-2005-008-00000-0 ) and KRF ( KRF-2008-313-C00501 and KRF-2008-313-C00508 ).

PY - 2009/10/28

Y1 - 2009/10/28

N2 - A coumarin-based dithiane (1) was synthesized for the selective detection of Hg2+ with respect to dual chromo- and fluorogenic changing events in an aqueous solution by the mercury-promoted transformation of a dithiane group into an aldehyde functional unit. The Hg2+-selective response of the chemodosimeter was clearly observed in aqueous buffer as well as in human blood plasma medium.

AB - A coumarin-based dithiane (1) was synthesized for the selective detection of Hg2+ with respect to dual chromo- and fluorogenic changing events in an aqueous solution by the mercury-promoted transformation of a dithiane group into an aldehyde functional unit. The Hg2+-selective response of the chemodosimeter was clearly observed in aqueous buffer as well as in human blood plasma medium.

KW - Chromogenic

KW - Coumarin

KW - Fluorogenic

KW - Mercury ion

UR - https://www.scopus.com/pages/publications/69749088784

U2 - 10.1016/j.tetlet.2009.08.045

DO - 10.1016/j.tetlet.2009.08.045

M3 - Article

AN - SCOPUS:69749088784

SN - 0040-4039

VL - 50

SP - 5958

EP - 5961

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 43

ER -

Fluorescent coumarinyldithiane as a selective chemodosimeter for mercury(II) ion in aqueous solution

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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