Fluorescent probes in public health and public safety

Hao Chu, Li Yang, Le Yu, Jungryun Kim, Jin Zhou, Mingle Li, Jong Seung Kim

Research output: Contribution to journalReview articlepeer-review

45 Citations (Scopus)


With the development of human civilization, the international situation is becoming more and more diversified and multipolar. Public health and safety issues have attracted increasing attention. To develop in situ, real-time and sensitive on-site detection technology is the key element to deal with public safety events. Fluorescent probes are increasingly used in the detection of public safety and public health due to their high selectivity, rapid response and simplicity. Based on the existing knowledge and our experiences, in this review, we comprehensively discuss the molecular design approaches of fluorescence probes in the field of public safety and health, and highlight the state-of-the-art paradigms in analytes detection, such as various narcotics, food additives, latent fingerprints, explosives and poisons. Moreover, the challenges and issues that need to be addressed in the future and a perspective in this research field are also provided. We hope this Review will give a general guidance and complementary insights for the future development of intelligently designed fluorescent probes, spurring the use in practice.

Original languageEnglish
Article number214208
JournalCoordination Chemistry Reviews
Publication statusPublished - 2021 Dec 15

Bibliographical note

Funding Information:
We are grateful for the financial support from the National Natural Science Foundation of China (No. 21705120 ), the Project of Shandong Province Higher Educational Outstanding Youth Innovation Team (No. 2019KJM008 ), the Natural Science Foundation of Shandong Province, China (No. ZR2017LB016 ), the Project of Shandong Province Higher Educational Science and Technology Program (No. J17KB074 ). We also thank for the support of Brain Pool Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (Grant No. 2020H1D3A1A02080172 , M.L.). This work was also supported by the National Research Foundation of Korea (CRI project no. 2018R1A3B1052702, NRF-2019M3E5D1A01068998, J.S.K)

Publisher Copyright:
© 2021 Elsevier B.V.


  • Fluorescent probe
  • Imaging
  • Public health
  • Public safety
  • Sensor

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry


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