Fluorescent sensing of pyrophosphate and ATP in 100% aqueous solution using a fluorescein derivative and Mn2+

K. M K Swamy; Soo Kyung Kwon; Ha Na Lee; S. M. Shantha Kumar; Jong Seung Kim; Juyoung Yoon

doi:10.1016/j.tetlet.2007.10.022

Fluorescent sensing of pyrophosphate and ATP in 100% aqueous solution using a fluorescein derivative and Mn²⁺

K. M K Swamy, Soo Kyung Kwon, Ha Na Lee, S. M. Shantha Kumar, Jong Seung Kim, Juyoung Yoon

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

A new fluorescein derivative has been synthesized for the detection of pyrophosphate (PPi) and ATP in 100% aqueous solution. Chemosensor 1 in the presence of Mn²⁺ (2.5 equiv) displayed selective fluorescent enhancements with PPi and ATP at pH 7.4. among the anions examined. The association constant of 1 in the presence of Mn²⁺ with PPi and ATP was calculated as 4.2 × 10⁴ and 3.5 × 10⁴ M^-1.

Original language	English
Pages (from-to)	8683-8686
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2007.10.022
Publication status	Published - 2007 Dec 3

Bibliographical note

Funding Information:
This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant (NRL) funded by the Korean government (MOST) (R04-2007-000-2007-0), the SRC program of the KOSEF (R11-2005-008-02001-0), Korea Ministry of Environment as ‘The Eco-technopia 21 project’ and BK21.

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2007.10.022

Cite this

@article{a46e9b2d87ee4e08a72bb45c224200ca,

title = "Fluorescent sensing of pyrophosphate and ATP in 100% aqueous solution using a fluorescein derivative and Mn2+",

abstract = "A new fluorescein derivative has been synthesized for the detection of pyrophosphate (PPi) and ATP in 100% aqueous solution. Chemosensor 1 in the presence of Mn2+ (2.5 equiv) displayed selective fluorescent enhancements with PPi and ATP at pH 7.4. among the anions examined. The association constant of 1 in the presence of Mn2+ with PPi and ATP was calculated as 4.2 × 104 and 3.5 × 104 M-1.",

author = "Swamy, {K. M K} and Kwon, {Soo Kyung} and Lee, {Ha Na} and {Shantha Kumar}, {S. M.} and Kim, {Jong Seung} and Juyoung Yoon",

note = "Funding Information: This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant (NRL) funded by the Korean government (MOST) (R04-2007-000-2007-0), the SRC program of the KOSEF (R11-2005-008-02001-0), Korea Ministry of Environment as {\textquoteleft}The Eco-technopia 21 project{\textquoteright} and BK21. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2007",

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doi = "10.1016/j.tetlet.2007.10.022",

language = "English",

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T1 - Fluorescent sensing of pyrophosphate and ATP in 100% aqueous solution using a fluorescein derivative and Mn2+

AU - Swamy, K. M K

AU - Kwon, Soo Kyung

AU - Lee, Ha Na

AU - Shantha Kumar, S. M.

AU - Kim, Jong Seung

AU - Yoon, Juyoung

N1 - Funding Information: This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant (NRL) funded by the Korean government (MOST) (R04-2007-000-2007-0), the SRC program of the KOSEF (R11-2005-008-02001-0), Korea Ministry of Environment as ‘The Eco-technopia 21 project’ and BK21. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2007/12/3

Y1 - 2007/12/3

N2 - A new fluorescein derivative has been synthesized for the detection of pyrophosphate (PPi) and ATP in 100% aqueous solution. Chemosensor 1 in the presence of Mn2+ (2.5 equiv) displayed selective fluorescent enhancements with PPi and ATP at pH 7.4. among the anions examined. The association constant of 1 in the presence of Mn2+ with PPi and ATP was calculated as 4.2 × 104 and 3.5 × 104 M-1.

AB - A new fluorescein derivative has been synthesized for the detection of pyrophosphate (PPi) and ATP in 100% aqueous solution. Chemosensor 1 in the presence of Mn2+ (2.5 equiv) displayed selective fluorescent enhancements with PPi and ATP at pH 7.4. among the anions examined. The association constant of 1 in the presence of Mn2+ with PPi and ATP was calculated as 4.2 × 104 and 3.5 × 104 M-1.

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