Abstract
A naphthalimide-based water soluble Zn 2+ sensor bearing polyamino carboxylate as a metal chelating moiety was synthesized and its application for the selective detection of Zn 2+ ion in 100% aqueous solution is demonstrated. The newly developed fluorescent sensor exhibits selective binding affinity towards Zn 2+ and pH insensitivity in biologically relevant range. Confocal fluorescent microscopy images indicate that this probe works effectively for intracellular Zn 2+ imaging with high cell permeability.
Original language | English |
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Pages (from-to) | 1489-1493 |
Number of pages | 5 |
Journal | Sensors and Actuators, B: Chemical |
Volume | 160 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2011 Dec 15 |
Keywords
- Cell imaging
- DFT calculations
- Fluorescent sensor
- Zinc
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Instrumentation
- Condensed Matter Physics
- Surfaces, Coatings and Films
- Metals and Alloys
- Electrical and Electronic Engineering
- Materials Chemistry