Focused fluorescent probe library for metal cations and biological anions

  • Hyun Woo Rhee
  • , Sang Wook Lee
  • , Jun Seok Lee
  • , Young Tae Chang*
  • , Jong In Hong
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A focused fluorescent probe library for metal cations was developed by combining metal chelators and picolinium/quinolinium moieties as combinatorial blocks connected through a styryl group. Furthermore, metal complexes derived from metal chelators having high binding affinities for metal cations were used to construct a focused probe library for phosphorylated biomolecules. More than 250 fluorescent probes were screened for identifying an ultraselective probe for dTTP.

Original languageEnglish
Pages (from-to)483-490
Number of pages8
JournalACS Combinatorial Science
Volume15
Issue number9
DOIs
Publication statusPublished - 2013 Sept 9
Externally publishedYes

Keywords

  • biological anions
  • fluorescent probe library
  • metal cations
  • thymidine

ASJC Scopus subject areas

  • General Chemistry

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