Functionality of Nonfunctional Diluent Ligands within Bicomponent Layers on Nanoparticles

Sohyun Seo, Jang Ho Joo, Do Hyun Park, Jae Seung Lee

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


The selective binding of nanoparticles to a specific entity is highly important for building assembly based superstructures and detecting various biomarkers and targets. Such type of binding can only be achieved by controlling the particle surface properties. Herein, we demonstrate the construction of a solid/liquid interfacial layer comprising multiple components on nanoparticle surfaces in order to obtain the desired binding properties. In addition to the actual binding components, the chemical structures of nonfunctional diluent ligands play a significant role in determining the overall binding properties of the nanoparticles. We also evaluated the binding properties of the nanoparticles coated with multiple components and optimized them by varying the interfacial coating conditions. Gold nanoparticles and single-stranded oligonucleotides are chosen as the core nanoparticles and coating functional ligands for model system, respectively, and examined in the presence of various chemical and biological diluents.

Original languageEnglish
Pages (from-to)13906-13915
Number of pages10
JournalJournal of Physical Chemistry C
Issue number25
Publication statusPublished - 2017 Jun 29

Bibliographical note

Funding Information:
This work was supported by the NRF funded by the Korean government, MSIP (NRF-2016R1A5A1010148, NRF- 2015M3A9D7031015, and NRF-2015R1C1A1A01053865). We thank Dr. Hionsuck Baik at the Korea Basic Science Institute (KBSI; Seoul, Republic of Korea) for his assistance with the TEM work for the AuNPs (data not shown).

Publisher Copyright:
© 2017 American Chemical Society.

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Energy(all)
  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films


Dive into the research topics of 'Functionality of Nonfunctional Diluent Ligands within Bicomponent Layers on Nanoparticles'. Together they form a unique fingerprint.

Cite this