Fundamental role of dendritic cells in inducing Th2 responses

Byoungjae Kim, Tae Hoon Kim

Research output: Contribution to journalReview articlepeer-review

24 Citations (Scopus)

Abstract

A mysterious puzzle in immunology is how the immune system decides what types of immune response to initiate against various stimuli. Although much is known about control of T helper 1 (Th1) and Th17 responses, the mechanisms that initiate Th2 responses remain obscure. Antigen-presenting cells, particularly dendritic cells (DCs), are mandatory for the induction of a Th cell response. Numerous studies have documented the organizing role of DCs in this process. The present review summarizes the fundamental roles of DCs in inducing Th2 responses.

Original languageEnglish
Pages (from-to)483-489
Number of pages7
JournalKorean Journal of Internal Medicine
Volume33
Issue number3
DOIs
Publication statusPublished - 2018 May

Keywords

  • Antigen-presenting cells
  • Dendritic cells
  • Th2 responses

ASJC Scopus subject areas

  • Internal Medicine

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