Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress

Ron Mittler; Yong Sig Kim; Luhua Song; Jesse Coutu; Alicia Coutu; Sultan Ciftci-Yilmaz; Hojoung Lee; Becky Stevenson; Jian Kang Zhu

doi:10.1016/j.febslet.2006.11.002

Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress

Ron Mittler, Yong Sig Kim, Luhua Song, Jesse Coutu, Alicia Coutu, Sultan Ciftci-Yilmaz, Hojoung Lee, Becky Stevenson, Jian Kang Zhu

Research output: Contribution to journal › Article › peer-review

353 Citations (Scopus)

Abstract

C₂H₂-zinc finger proteins that contain the EAR repressor domain are thought to play a key role in modulating the defense response of plants to abiotic stress. Constitutive expression of the C₂H₂-EAR zinc finger protein Zat10 in Arabidopsis was found to elevate the expression of reactive oxygen-defense transcripts and to enhance the tolerance of plants to salinity, heat and osmotic stress. Surprisingly, knockout and RNAi mutants of Zat10 were also more tolerant to osmotic and salinity stress. Our results suggest that Zat10 plays a key role as both a positive and a negative regulator of plant defenses.

Original language	English
Pages (from-to)	6537-6542
Number of pages	6
Journal	FEBS Letters
Volume	580
Issue number	28-29
DOIs	https://doi.org/10.1016/j.febslet.2006.11.002
Publication status	Published - 2006 Dec 11
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by funding from The National Science Foundation (IBN-0420033, IBN-0420152 and NSF-0431327), National Institute of Health (R01GM059138) and The Nevada Agricultural Experimental Station (Publication number 03055517).

Keywords

Abiotic stress
Arabidopsis thaliana
CH-zinc finger
EAR motif
Stress tolerance
Zat10

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/j.febslet.2006.11.002

Cite this

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title = "Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress",

abstract = "C2H2-zinc finger proteins that contain the EAR repressor domain are thought to play a key role in modulating the defense response of plants to abiotic stress. Constitutive expression of the C2H2-EAR zinc finger protein Zat10 in Arabidopsis was found to elevate the expression of reactive oxygen-defense transcripts and to enhance the tolerance of plants to salinity, heat and osmotic stress. Surprisingly, knockout and RNAi mutants of Zat10 were also more tolerant to osmotic and salinity stress. Our results suggest that Zat10 plays a key role as both a positive and a negative regulator of plant defenses.",

keywords = "Abiotic stress, Arabidopsis thaliana, CH-zinc finger, EAR motif, Stress tolerance, Zat10",

author = "Ron Mittler and Kim, {Yong Sig} and Luhua Song and Jesse Coutu and Alicia Coutu and Sultan Ciftci-Yilmaz and Hojoung Lee and Becky Stevenson and Zhu, {Jian Kang}",

note = "Funding Information: This work was supported by funding from The National Science Foundation (IBN-0420033, IBN-0420152 and NSF-0431327), National Institute of Health (R01GM059138) and The Nevada Agricultural Experimental Station (Publication number 03055517). ",

year = "2006",

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day = "11",

doi = "10.1016/j.febslet.2006.11.002",

language = "English",

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pages = "6537--6542",

journal = "FEBS Letters",

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T1 - Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress

AU - Mittler, Ron

AU - Kim, Yong Sig

AU - Song, Luhua

AU - Coutu, Jesse

AU - Coutu, Alicia

AU - Ciftci-Yilmaz, Sultan

AU - Lee, Hojoung

AU - Stevenson, Becky

AU - Zhu, Jian Kang

N1 - Funding Information: This work was supported by funding from The National Science Foundation (IBN-0420033, IBN-0420152 and NSF-0431327), National Institute of Health (R01GM059138) and The Nevada Agricultural Experimental Station (Publication number 03055517).

PY - 2006/12/11

Y1 - 2006/12/11

N2 - C2H2-zinc finger proteins that contain the EAR repressor domain are thought to play a key role in modulating the defense response of plants to abiotic stress. Constitutive expression of the C2H2-EAR zinc finger protein Zat10 in Arabidopsis was found to elevate the expression of reactive oxygen-defense transcripts and to enhance the tolerance of plants to salinity, heat and osmotic stress. Surprisingly, knockout and RNAi mutants of Zat10 were also more tolerant to osmotic and salinity stress. Our results suggest that Zat10 plays a key role as both a positive and a negative regulator of plant defenses.

AB - C2H2-zinc finger proteins that contain the EAR repressor domain are thought to play a key role in modulating the defense response of plants to abiotic stress. Constitutive expression of the C2H2-EAR zinc finger protein Zat10 in Arabidopsis was found to elevate the expression of reactive oxygen-defense transcripts and to enhance the tolerance of plants to salinity, heat and osmotic stress. Surprisingly, knockout and RNAi mutants of Zat10 were also more tolerant to osmotic and salinity stress. Our results suggest that Zat10 plays a key role as both a positive and a negative regulator of plant defenses.

KW - Abiotic stress

KW - Arabidopsis thaliana

KW - CH-zinc finger

KW - EAR motif

KW - Stress tolerance

KW - Zat10

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DO - 10.1016/j.febslet.2006.11.002

M3 - Article

C2 - 17112521

AN - SCOPUS:34447631354

SN - 0014-5793

VL - 580

SP - 6537

EP - 6542

JO - FEBS Letters

JF - FEBS Letters

IS - 28-29

ER -

Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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