Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma

Ji Hea Kim; Ji Hyeon Hong; Ka Won Kang; Byung Hyun Lee; Young Park; Byung Soo Kim

doi:10.1016/j.scr.2022.102939

Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma

Ji Hea Kim, Ji Hyeon Hong, Ka Won Kang, Byung Hyun Lee, Young Park, Byung Soo Kim

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies.

Original language	English
Article number	102939
Journal	Stem Cell Research
Volume	65
DOIs	https://doi.org/10.1016/j.scr.2022.102939
Publication status	Published - 2022 Dec

Bibliographical note

Funding Information:
This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HR14C0007).

Publisher Copyright:
© 2022

ASJC Scopus subject areas

Developmental Biology
Cell Biology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.scr.2022.102939

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title = "Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma",

abstract = "Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies.",

author = "Kim, {Ji Hea} and Hong, {Ji Hyeon} and Kang, {Ka Won} and Lee, {Byung Hyun} and Young Park and Kim, {Byung Soo}",

note = "Funding Information: This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HR14C0007). Publisher Copyright: {\textcopyright} 2022",

year = "2022",

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doi = "10.1016/j.scr.2022.102939",

language = "English",

volume = "65",

journal = "Stem Cell Research",

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AU - Kim, Ji Hea

AU - Hong, Ji Hyeon

AU - Kang, Ka Won

AU - Lee, Byung Hyun

AU - Park, Young

AU - Kim, Byung Soo

N1 - Funding Information: This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HR14C0007). Publisher Copyright: © 2022

PY - 2022/12

Y1 - 2022/12

N2 - Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies.

AB - Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies.

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VL - 65

JO - Stem Cell Research

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M1 - 102939

ER -

Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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