@article{da052b1f5aa3493f97da0697569d4865,
title = "Genetic diversity and phylogeography of Jeju Orthohantavirus (Hantaviridae) in the Republic of Korea",
abstract = "Orthohantaviruses are negative-sense, single-stranded RNA viruses harbored by rodents, shrews, moles, and bats. Of the shrew-borne orthohantaviruses in the Republic of Korea (ROK), Jeju orthohantavirus (Jeju virus, JJUV) was found on Jeju Island. This small-scale epidemiologic survey investigated the geographic distribution and molecular phylogeny of JJUV in the ROK. In 32 trapping sites, tissues of 84 Crocidura shantungensis were analyzed for JJUV RNA. JJUV RNA was detected in seven (8.3%) shrews captured on the Korean peninsula. The molecular epidemiologic survey demonstrated the prevalence of JJUV by geographic distribution. The RNA loads of JJUV were evaluated in various tissues. Entire coding sequences of tripartite genomes were recovered from two JJUV strains on the mainland. Phylogenetic relationships of the JJUV revealed a distinct geographic lineage of mainland strains from the strains on Jeju Island. This study sheds light on the molecular epidemiology, phylogeographic diversity, and virus-host co-divergence of JJUV, ROK.",
keywords = "Crocidura shantungensis, Epidemiologic survey, Jeju orthohantavirus, Korean peninsula, Phylogenetic analysis",
author = "Lee, {Seung Ho} and Kim, {Won Keun} and Kyungmin Park and No, {Jin Sun} and Lee, {Geum Young} and Kim, {Heung Chul} and Klein, {Terry A.} and Min, {Mi Sook} and Lee, {Seo Jin} and Jusun Hwang and Park, {Man Seong} and Song, {Jin Won}",
note = "Funding Information: We thank Mr. Su Am Kim for animal trapping and experimental support. This work was supported by the Research Program to Solve Social Issues of the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT ( NRF-2017M3A9E4061992 ), the Institute of Biomedical Science & Food Safety, Korea University ( K1808091 ), and the Armed Forces Health Surveillance Branch, Global Emerging Infections Surveillance and Response System (AFHSB-GEIS), Silver Spring, MD (ProMIS ID #P0122-19-ME-03 ). Funding Information: We thank Mr. Su Am Kim for animal trapping and experimental support. This work was supported by the Research Program to Solve Social Issues of the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (NRF-2017M3A9E4061992), the Institute of Biomedical Science & Food Safety, Korea University (K1808091), and the Armed Forces Health Surveillance Branch, Global Emerging Infections Surveillance and Response System (AFHSB-GEIS), Silver Spring, MD (ProMIS ID #P0122-19-ME-03). Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = apr,
doi = "10.1016/j.virol.2020.01.012",
language = "English",
volume = "543",
pages = "13--19",
journal = "Virology",
issn = "0042-6822",
publisher = "Academic Press Inc.",
}