Global Distribution of Rubella Virus Genotypes

Du Ping Zheng; Teryl K. Frey; Joseph Icenogle; Shigetaka Katow; Emily S. Abernathy; Ki Joon Song; Wen Bo Xu; Vitaly Yarulin; R. G. Desjatskova; Yair Aboudy; Gisela Enders; Margaret Croxson

doi:10.3201/eid0912.030242

Global Distribution of Rubella Virus Genotypes

Du Ping Zheng, Teryl K. Frey, Joseph Icenogle, Shigetaka Katow, Emily S. Abernathy, Ki Joon Song, Wen Bo Xu, Vitaly Yarulin, R. G. Desjatskova, Yair Aboudy, Gisela Enders, Margaret Croxson

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Abstract

Phylogenetic analysis of a collection of 103 E1 gene sequences from rubella viruses isolated from 17 countries from 1961 to 2000 confirmed the existence of at least two genotypes. Rubella genotype I (RGI) isolates, predominant in Europe, Japan, and the Western Hemisphere, segregated into discrete subgenotypes; international subgenotypes present in the 1960s and 1970s were replaced by geographically restricted subgenotypes after ∼1980. Recently, active subgenotypes include one in the United States and Latin America, one in China, and a third that apparently originated in Asia and spread to Europe and North America, starting in 1997, indicating the recent emergence of an international subgenotype. A virus that potentially arose as a recombinant between two RGI subgenotypes was discovered. Rubella genotype II (RGII) showed greater genetic diversity than did RGI and may actually consist of multiple genotypes. RGII viruses were limited to Asia and Europe; RGI viruses were also present in most of the countries where RGII viruses were isolated.

Original language	English
Pages (from-to)	1523-1530
Number of pages	8
Journal	Emerging Infectious Diseases
Volume	9
Issue number	12
DOIs	https://doi.org/10.3201/eid0912.030242
Publication status	Published - 2003 Dec
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3201/eid0912.030242

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title = "Global Distribution of Rubella Virus Genotypes",

abstract = "Phylogenetic analysis of a collection of 103 E1 gene sequences from rubella viruses isolated from 17 countries from 1961 to 2000 confirmed the existence of at least two genotypes. Rubella genotype I (RGI) isolates, predominant in Europe, Japan, and the Western Hemisphere, segregated into discrete subgenotypes; international subgenotypes present in the 1960s and 1970s were replaced by geographically restricted subgenotypes after ∼1980. Recently, active subgenotypes include one in the United States and Latin America, one in China, and a third that apparently originated in Asia and spread to Europe and North America, starting in 1997, indicating the recent emergence of an international subgenotype. A virus that potentially arose as a recombinant between two RGI subgenotypes was discovered. Rubella genotype II (RGII) showed greater genetic diversity than did RGI and may actually consist of multiple genotypes. RGII viruses were limited to Asia and Europe; RGI viruses were also present in most of the countries where RGII viruses were isolated.",

author = "Zheng, {Du Ping} and Frey, {Teryl K.} and Joseph Icenogle and Shigetaka Katow and Abernathy, {Emily S.} and Song, {Ki Joon} and Xu, {Wen Bo} and Vitaly Yarulin and Desjatskova, {R. G.} and Yair Aboudy and Gisela Enders and Margaret Croxson",

year = "2003",

month = dec,

doi = "10.3201/eid0912.030242",

language = "English",

volume = "9",

pages = "1523--1530",

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AU - Zheng, Du Ping

AU - Frey, Teryl K.

AU - Icenogle, Joseph

AU - Katow, Shigetaka

AU - Abernathy, Emily S.

AU - Song, Ki Joon

AU - Xu, Wen Bo

AU - Yarulin, Vitaly

AU - Desjatskova, R. G.

AU - Aboudy, Yair

AU - Enders, Gisela

AU - Croxson, Margaret

PY - 2003/12

Y1 - 2003/12

N2 - Phylogenetic analysis of a collection of 103 E1 gene sequences from rubella viruses isolated from 17 countries from 1961 to 2000 confirmed the existence of at least two genotypes. Rubella genotype I (RGI) isolates, predominant in Europe, Japan, and the Western Hemisphere, segregated into discrete subgenotypes; international subgenotypes present in the 1960s and 1970s were replaced by geographically restricted subgenotypes after ∼1980. Recently, active subgenotypes include one in the United States and Latin America, one in China, and a third that apparently originated in Asia and spread to Europe and North America, starting in 1997, indicating the recent emergence of an international subgenotype. A virus that potentially arose as a recombinant between two RGI subgenotypes was discovered. Rubella genotype II (RGII) showed greater genetic diversity than did RGI and may actually consist of multiple genotypes. RGII viruses were limited to Asia and Europe; RGI viruses were also present in most of the countries where RGII viruses were isolated.

AB - Phylogenetic analysis of a collection of 103 E1 gene sequences from rubella viruses isolated from 17 countries from 1961 to 2000 confirmed the existence of at least two genotypes. Rubella genotype I (RGI) isolates, predominant in Europe, Japan, and the Western Hemisphere, segregated into discrete subgenotypes; international subgenotypes present in the 1960s and 1970s were replaced by geographically restricted subgenotypes after ∼1980. Recently, active subgenotypes include one in the United States and Latin America, one in China, and a third that apparently originated in Asia and spread to Europe and North America, starting in 1997, indicating the recent emergence of an international subgenotype. A virus that potentially arose as a recombinant between two RGI subgenotypes was discovered. Rubella genotype II (RGII) showed greater genetic diversity than did RGI and may actually consist of multiple genotypes. RGII viruses were limited to Asia and Europe; RGI viruses were also present in most of the countries where RGII viruses were isolated.

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SN - 1080-6040

VL - 9

SP - 1523

EP - 1530

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 12

ER -

Global Distribution of Rubella Virus Genotypes

Abstract

ASJC Scopus subject areas

UN SDGs

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