Abstract
A very convenient colorimetric method for the identification of single nucleotide polymorphism was developed utilizing gold nanoparticles and an allele-specific polymerase chain reaction and its diagnostic capability was successfully verified by correctly identifying various mutations in the BRCA1 gene.
Original language | English |
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Pages (from-to) | 1062-1065 |
Number of pages | 4 |
Journal | IFMBE Proceedings |
Volume | 37 |
DOIs | |
Publication status | Published - 2011 |
Externally published | Yes |
Keywords
- BRCA
- Single nucleotide polymorphism (SNP)
- allelespecific PCR
- gold nanoparticles
- thiolated primer
ASJC Scopus subject areas
- Bioengineering
- Biomedical Engineering