Owing to their excellent surface plasmonic properties, Au nanobranches have drawn increasing attention in various bioapplications, such as contrast agents for photoacoustic imaging, nanomedicines for photothermal therapy, and carriers for drug delivery. The monodispersity and plasmonic bandwidth of Au nanobranches are of great importance for the efficacy of those bioapplications. However, it is still a challenge to accurately synthesize size- and shape-controlled Au nanobranches. Here we report a facile seed-mediated growth method to synthesize monodisperse Au nanotetrapods (NTPs) with tunable and ultranarrow plasmonic bands. The NTPs have a novel D2d symmetry with four arms elongated in four 110»directions. The growth mechanism of NTPs relies on the delicate kinetic control of deposition and diffusion rates of adatoms. Upon laser irradiation, the PEGylated NTPs possess remarkable photothermal conversion efficiencies and photoacoustic imaging properties. The NTPs can be applied as a multifunctional theranostic agent for both photoacoustic imaging and image-guided photothermal therapy.
Bibliographical noteFunding Information:
K.L. thanks the National Natural Science Foundation of China (21674042 and 21474040) for financial support. K.L. and Z.-Y.L. gratefully acknowledge financial support from the National Natural Science Foundation of China (21534004). K.L. and T.S. thank the Interdisciplinary Innovation Project of the First Hospital of Jilin University (JDYYJCHX001). This work is also supported by Program for JLU Science and Technology Innovative Research Team “JLUSTIRT2017TD-06” and the opening funds of State Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Science. S.L. acknowledges support from the Robert A. Welch Foundation (C-1664) and the National Science Foundation (CHE1507745). Q.Z. acknowledges support from the Smalley-Curl Institute at Rice University through a J Evans Attwell-Welch Postdoctoral Fellowship.
© 2019 American Chemical Society.
ASJC Scopus subject areas
- Materials Science(all)
- Physical and Theoretical Chemistry