Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer

Andrew Ahn, Changhuei Yang, Adam Wax, Gabriel Popescu, Christopher Fang-Yen, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach-Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples.

Original languageEnglish
Pages (from-to)1188-1190
Number of pages3
JournalApplied optics
Issue number7
Publication statusPublished - 2005 Mar 1

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering


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