Hemodynamic analysis of coronary artery microcirculation using a pig's morphometric data

Sehyun Shin, Jungsu Park

Research output: Contribution to journalArticlepeer-review


Stenosed coronary artery may play an important role in various coronary heart diseases. However, it has not been known how much stenosed coronary artery affects coronary circulation system, quantitatively. The present study developed a mathematical model for microcirculation in the left common coronary artery (LCCA) with adopting a previously measured morphological data and mechanical properties of the coronary vessels. We examine the effect of percent diameter stenosis on blood flow rate and shear stress for two cases. Case I comprised of onestenosed element at 10th order (% diameter stenosis are 10, 30, and 50, respectively). Case II consisted of completely occluded element at 10th order (number of occluded elements are 0, 1, and 2 out of 8, respectively). As the level of stenosis becomes severe, the shear stress increases significantly but the flow rate reduction was relatively small. However, for the occluded case, there was linearly proportional reduction of flow rate according to number of occluded elements. Either such high shear stress associated with coronary artery stenosis or reduced flow rate due to occlusion may cause atherosclerosis and myocardial ischemia.

Original languageEnglish
Pages (from-to)1313-1320
Number of pages8
JournalJournal of Mechanical Science and Technology
Issue number6
Publication statusPublished - 2005 Jun
Externally publishedYes

Bibliographical note

Funding Information:
This work is sponsored by Grants (R05-2003-000-11752) from the KOSEF.


  • Hemodynamics
  • Left common Coronary Artery (LCCA)
  • Occlusion
  • Stenosis

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering


Dive into the research topics of 'Hemodynamic analysis of coronary artery microcirculation using a pig's morphometric data'. Together they form a unique fingerprint.

Cite this