Hepatic and pulmonary nodular lesions in pediatric urinary tract infections

Hyung Eun Yim, Byung Min Choi, Young Jun Rhie, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee

    Research output: Contribution to journalArticlepeer-review


    One of the major goals in investigating children with urinary tract infection (UTI) is to recognize patients at risk of further UTI-related problems. This study reports the clinical features of 19 pediatric patients with UTIs in whom associated hepatic and/or pulmonary nodules were incidentally diagnosed by the imaging tests performed for the UTI. Hepatic nodules in five patients were detected on ultrasound scans, and pulmonary nodules and both hepatic and pulmonary nodules were detected in 12 and two children by dimercaptosuccinic acid scintigraphy. The mean age of the patients was 24.5 months. Vesicoureteral reflux (VUR) was detected in nine of 17 patients (52.9%), acute pyelonephritis was identified in nine of 18 patients, and renal scarring was found in 57.1% patients with pyelonephritis. On follow-up, the hepatic and/or pulmonary nodules regressed in all patients. About 85.7% of patients experienced a recurrence of UTI within 1 year. In comparison with age- and sex-matched controls with UTIs without pulmonary or hepatic nodules, the presence of VUR and the recurrence of UTI within 1 year were higher in patients with UTIs and nodules (P∈<∈0.05). The hepatic and/or pulmonary nodules identified on the ultrasound scan and by dimercaptosuccinic acid scintigraphy may provide a valuable diagnostic marker for the proper management of patients with an UTI.

    Original languageEnglish
    Pages (from-to)425-431
    Number of pages7
    JournalPediatric Nephrology
    Issue number3
    Publication statusPublished - 2011 Mar


    • Child
    • Risk assessment
    • Technetium Tc 99 m dimercaptosuccinic acid
    • Ultrasonography
    • Urinary tract infection

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Nephrology


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