TY - GEN
T1 - High-sensitive, direct and label-free detection technique of nanotoxic material using QCM
AU - Park, Chanho
AU - Jang, Kuewhan
AU - Lee, Sangmyung
AU - You, Juneseok
AU - Park, Jinsung
AU - Na, Sungsoo
N1 - Funding Information:
This study was supported by the National Research Foundation of Korea (NRF) under grant numbers of NRF- 2012-0000785, NRF-2012-0006646,NRF- 2014R1A2A1A11052389 and NRF-2013R1A1A1058102 funded by the Ministry of Science, ICT & Future Planning.
Publisher Copyright:
Copyright 2015 by TechConnect. All rights reserved.
PY - 2015
Y1 - 2015
N2 - For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial in real life. However, high toxicity of those materials has been reported and the detection method is required for human health and environment. In present study, high-sensitive, label-free detection methods of nanotoxic materials are described. We have developed a sensitive and selective quart crystal microbalance (QCM) based sensor for detection of nanotoxic materials by using frequency shift. In this study, we propose the sensitive in situ detection of nanotoxic materials by using QCM functionalized with a specific DNA for a target material. It also allows the detection of target material rapidly in real time. In contrast to the conventional methods, this method is label-free and sensitive, capable of direct rapid detection and real-time monitoring. The results suggest that QCM-based detection opens a new avenue for the development of a practical water-testing sensor.
AB - For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial in real life. However, high toxicity of those materials has been reported and the detection method is required for human health and environment. In present study, high-sensitive, label-free detection methods of nanotoxic materials are described. We have developed a sensitive and selective quart crystal microbalance (QCM) based sensor for detection of nanotoxic materials by using frequency shift. In this study, we propose the sensitive in situ detection of nanotoxic materials by using QCM functionalized with a specific DNA for a target material. It also allows the detection of target material rapidly in real time. In contrast to the conventional methods, this method is label-free and sensitive, capable of direct rapid detection and real-time monitoring. The results suggest that QCM-based detection opens a new avenue for the development of a practical water-testing sensor.
KW - Label-free detection
KW - Nanomaterial
KW - Quart crystal microbalance
KW - Resonance frequency
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=84983395780&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84983395780
T3 - NSTI: Advanced Materials - TechConnect Briefs 2015
SP - 180
EP - 182
BT - NSTI
A2 - Laudon, Matthew
A2 - Romanowicz, Bart
PB - Taylor and Francis Inc.
T2 - 10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference
Y2 - 14 June 2015 through 17 June 2015
ER -
