High-sensitive, direct and label-free detection technique of nanotoxic material using QCM

Chanho Park; Kuewhan Jang; Sangmyung Lee; Juneseok You; Jinsung Park; Sungsoo Na

High-sensitive, direct and label-free detection technique of nanotoxic material using QCM

Chanho Park, Kuewhan Jang, Sangmyung Lee, Juneseok You, Jinsung Park, Sungsoo Na

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial in real life. However, high toxicity of those materials has been reported and the detection method is required for human health and environment. In present study, high-sensitive, label-free detection methods of nanotoxic materials are described. We have developed a sensitive and selective quart crystal microbalance (QCM) based sensor for detection of nanotoxic materials by using frequency shift. In this study, we propose the sensitive in situ detection of nanotoxic materials by using QCM functionalized with a specific DNA for a target material. It also allows the detection of target material rapidly in real time. In contrast to the conventional methods, this method is label-free and sensitive, capable of direct rapid detection and real-time monitoring. The results suggest that QCM-based detection opens a new avenue for the development of a practical water-testing sensor.

Original language	English
Title of host publication	NSTI
Subtitle of host publication	Biotech, Biomaterials and Biomedical - TechConnect Briefs 2015
Editors	Matthew Laudon, Bart Romanowicz
Publisher	Taylor and Francis Inc.
Pages	180-182
Number of pages	3
ISBN (Electronic)	9781498747295
Publication status	Published - 2015
Event	10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference - Washington, United States Duration: 2015 Jun 14 → 2015 Jun 17

Publication series

Name	NSTI: Advanced Materials - TechConnect Briefs 2015
Volume	3

Other

Other	10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference
Country/Territory	United States
City	Washington
Period	15/6/14 → 15/6/17

Bibliographical note

Funding Information:
This study was supported by the National Research Foundation of Korea (NRF) under grant numbers of NRF- 2012-0000785, NRF-2012-0006646,NRF- 2014R1A2A1A11052389 and NRF-2013R1A1A1058102 funded by the Ministry of Science, ICT & Future Planning.

Publisher Copyright:
Copyright 2015 by TechConnect. All rights reserved.

Keywords

Label-free detection
Nanomaterial
Quart crystal microbalance
Resonance frequency
Toxicity

ASJC Scopus subject areas

Surfaces, Coatings and Films
Fluid Flow and Transfer Processes
Biotechnology
Fuel Technology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

High-sensitive, direct and label-free detection technique of nanotoxic material using QCM. / Park, Chanho; Jang, Kuewhan; Lee, Sangmyung et al.
NSTI: Biotech, Biomaterials and Biomedical - TechConnect Briefs 2015. ed. / Matthew Laudon; Bart Romanowicz. Taylor and Francis Inc., 2015. p. 180-182 (NSTI: Advanced Materials - TechConnect Briefs 2015; Vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Park, C, Jang, K, Lee, S, You, J, Park, J & Na, S 2015, High-sensitive, direct and label-free detection technique of nanotoxic material using QCM. in M Laudon & B Romanowicz (eds), NSTI: Biotech, Biomaterials and Biomedical - TechConnect Briefs 2015. NSTI: Advanced Materials - TechConnect Briefs 2015, vol. 3, Taylor and Francis Inc., pp. 180-182, 10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference, Washington, United States, 15/6/14.

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N2 - For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial in real life. However, high toxicity of those materials has been reported and the detection method is required for human health and environment. In present study, high-sensitive, label-free detection methods of nanotoxic materials are described. We have developed a sensitive and selective quart crystal microbalance (QCM) based sensor for detection of nanotoxic materials by using frequency shift. In this study, we propose the sensitive in situ detection of nanotoxic materials by using QCM functionalized with a specific DNA for a target material. It also allows the detection of target material rapidly in real time. In contrast to the conventional methods, this method is label-free and sensitive, capable of direct rapid detection and real-time monitoring. The results suggest that QCM-based detection opens a new avenue for the development of a practical water-testing sensor.

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High-sensitive, direct and label-free detection technique of nanotoxic material using QCM

Abstract

Publication series

Other

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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Cite this