Abstract
Summary: Advances in lab-on-a-chip technologies enabled programmable, reconfigurable, and scalable manipulation of a variety of laboratory procedures. Samples, reagents, and fluids can be precisely controlled; buffer temperature, pH, and concentration control systems as well as a variety of detection systems can be integrated on a small chip. These advantages have attracted attention in various fields of clinical application including leukemia diagnosis and research. A lot of research on lab-on-a-chip based diagnosis has been reported and the field is rapidly expanding. This review describes recent developments of lab-on-a-chip technologies as solutions to challenges for high-throughput leukemia diagnosis.
Original language | English |
---|---|
Pages (from-to) | 480-490 |
Number of pages | 11 |
Journal | International Journal of Laboratory Hematology |
Volume | 35 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2013 Oct |
Keywords
- Diagnosis
- High-throughput screening
- Lab-on-a-chip
- Leukemia
- Microfluidics
ASJC Scopus subject areas
- Hematology
- Clinical Biochemistry
- Biochemistry, medical