Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi

Jun Feng Zhang; Lin E. Guo; Tie Nan Zang; Yu Lian Duan; Xin Yi Liu; Zhigang Yang; Peter Verwilst; Kaijun Luo; Guang Ke Wang; Jun Feng Kou; Ying Zhou; Jong Seung Kim

doi:10.1002/asia.201500091

Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PP_i

Jun Feng Zhang, Lin E. Guo, Tie Nan Zang, Yu Lian Duan, Xin Yi Liu, Zhigang Yang, Peter Verwilst, Kaijun Luo, Guang Ke Wang, Jun Feng Kou, Ying Zhou, Jong Seung Kim

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

A chemodosimeter was designed to function as a highly selective phosphate ion (P_i) sensor, showing a 91-fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase-catalyzed P_i generation and was the first probe able to trace the generation and enrichment of P_i through hemichannel closure in Sf9 cells.

Original language	English
Pages (from-to)	1165-1169
Number of pages	5
Journal	Chemistry - An Asian Journal
Volume	10
Issue number	5
DOIs	https://doi.org/10.1002/asia.201500091
Publication status	Published - 2015 May 1

Bibliographical note

Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords

1 8-naphthalene imide
fluorescent probes
in vivo imaging
inorganic phosphate
sensors

ASJC Scopus subject areas

General Chemistry
Biochemistry
Organic Chemistry

Access to Document

10.1002/asia.201500091

Cite this

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title = "Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi",

abstract = "A chemodosimeter was designed to function as a highly selective phosphate ion (Pi) sensor, showing a 91-fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase-catalyzed Pi generation and was the first probe able to trace the generation and enrichment of Pi through hemichannel closure in Sf9 cells.",

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AU - Zhang, Jun Feng

AU - Guo, Lin E.

AU - Zang, Tie Nan

AU - Duan, Yu Lian

AU - Liu, Xin Yi

AU - Yang, Zhigang

AU - Verwilst, Peter

AU - Luo, Kaijun

AU - Wang, Guang Ke

AU - Kou, Jun Feng

AU - Zhou, Ying

AU - Kim, Jong Seung

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