Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi

Jun Feng Zhang, Lin E. Guo, Tie Nan Zang, Yu Lian Duan, Xin Yi Liu, Zhigang Yang, Peter Verwilst, Kaijun Luo, Guang Ke Wang, Jun Feng Kou, Ying Zhou, Jong Seung Kim

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    A chemodosimeter was designed to function as a highly selective phosphate ion (Pi) sensor, showing a 91-fold ratiometric fluorescence enhancement. The probe successfully visualized exogenous and endogenous apyrase-catalyzed Pi generation and was the first probe able to trace the generation and enrichment of Pi through hemichannel closure in Sf9 cells.

    Original languageEnglish
    Pages (from-to)1165-1169
    Number of pages5
    JournalChemistry - An Asian Journal
    Volume10
    Issue number5
    DOIs
    Publication statusPublished - 2015 May 1

    Bibliographical note

    Publisher Copyright:
    © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

    Keywords

    • 1 8-naphthalene imide
    • fluorescent probes
    • in vivo imaging
    • inorganic phosphate
    • sensors

    ASJC Scopus subject areas

    • General Chemistry
    • Biochemistry
    • Organic Chemistry

    Fingerprint

    Dive into the research topics of 'Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi'. Together they form a unique fingerprint.

    Cite this