Hollow porous poly(ε-caprolactone) microspheres by emulsion solvent extraction

Tae Sik Jang, Eun Jung Lee, Hyoun Ee Kim, Young Hag Koh

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Hollow porous poly (ε-caprolactone) microspheres with different structures were prepared using a solvent/non-solvent emulsion solvent extraction technique. The PCL concentration is an important factor for controlling the structure of hollow PCL microspheres. Hollow PCL microspheres with a porous polymer shell were formed when the polymer concentration was appropriate (12% w/v), whereas porous microspheres were produced when the polymer concentration was too high (20% w/v). The ability to incorporate silica xerogels into the PCL hollow microspheres was examined by scanning electron microscopy. These PCL hollow porous microspheres have potential applications in the local delivery of proteins and drugs.

Original languageEnglish
Pages (from-to)157-159
Number of pages3
JournalMaterials Letters
Volume72
DOIs
Publication statusPublished - 2012 Apr 1

Bibliographical note

Funding Information:
This work was supported by the Technology Innovation Program (Contract No. 10037915 , WPM Biomedical Materials–Implant Materials) funded by the Ministry of Knowledge Economy (MKE, Korea) .

Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.

Keywords

  • Biodegradable
  • Hollow microsphere
  • Poly(ε-caprolactone)
  • Porous

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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