Hydrazine exposé: The next-generation fluorescent probe

Yuna Jung, In Gyoung Ju, Young Ho Choe, Youngseo Kim, Sungnam Park, Young Min Hyun, Myung Sook Oh, Dokyoung Kim

Research output: Contribution to journalArticlepeer-review

94 Citations (Scopus)


Hydrazine (N 2 H 4 ) is one of the most important pnictogen hydride chemicals, and is utilized within a wide spectrum of industries. As a result of its extensive use, hydrazine's monitoring methods have constantly come under fire due to its potential health risk and the subsequent environmental pollution. Fluorometric molecular sensing systems generally report with a major emphasis on the merit of fluorescence analysis. What we are proposing within this report is a next-generation fluorescent probe that allows hydrazine to become fully traceable, within multifarious environments that show fast and intuitional fluorescence transformation. A new sensing moiety, ortho-methoxy-methyl-ether (o-OMOM) incorporated electron donor (D)-Acceptor (A) type naphthaldehyde provides high selectivity and sensitivity amidst its superiority within practical applications for sensing hydrazine. The new probe overcomes most of the drawbacks of currently used fluorescent probes, and due to its successful demonstrations, such as real-Time spray-based sensing, soil analysis, and two-photon tissue imaging, its potential for practical application is beyond reproach.

Original languageEnglish
Pages (from-to)441-449
Number of pages9
JournalACS Sensors
Issue number2
Publication statusPublished - 2019 Feb 22
Externally publishedYes


  • chemical sensor
  • fluorescent probe
  • hydrazine
  • hydrazone-formation
  • two-photon tissue imaging

ASJC Scopus subject areas

  • Bioengineering
  • Instrumentation
  • Process Chemistry and Technology
  • Fluid Flow and Transfer Processes


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