TY - JOUR
T1 - Iatrogenic Mycobacterium abscessus infection associated with acupuncture
T2 - Clinical manifestations and its treatment
AU - Ryu, Hwa Jung
AU - Kim, Woo Joo
AU - Oh, Chil Hwan
AU - Song, Hae J.
PY - 2005/10
Y1 - 2005/10
N2 - Background: Mycobacterial infections transmitted by acupuncture are an emerging problem. There have been two reports of mycobacterial infections complicating acupuncture in the English literature. Aim: To describe the clinical manifestations and treatment of patients who acquired localized Mycobacterium abscessus infection in the process of acupuncture. Methods: Clinical manifestations and responses to different methods of treatment were reviewed in 40 patients who developed various skin lesions after acupuncture at a Korean oriental medicine clinic. Results: The morphology of the lesions which developed at the acupuncture sites varied. Although the lesions disappeared with the combined administration of clarithromycin and amikacin for 3 months in most cases, five out of 25 patients (20%) showed residual lesions at the end of treatment, and had to be treated with a higher dosage of clarithromycin or alternative antibiotics based on sensitivity tests. Conclusions: We recommend at least 3 months of treatment with clarithromycin for treating skin infections caused by M. abscessus, with supplementary antibiotics selected based on patients' drug sensitivity tests.
AB - Background: Mycobacterial infections transmitted by acupuncture are an emerging problem. There have been two reports of mycobacterial infections complicating acupuncture in the English literature. Aim: To describe the clinical manifestations and treatment of patients who acquired localized Mycobacterium abscessus infection in the process of acupuncture. Methods: Clinical manifestations and responses to different methods of treatment were reviewed in 40 patients who developed various skin lesions after acupuncture at a Korean oriental medicine clinic. Results: The morphology of the lesions which developed at the acupuncture sites varied. Although the lesions disappeared with the combined administration of clarithromycin and amikacin for 3 months in most cases, five out of 25 patients (20%) showed residual lesions at the end of treatment, and had to be treated with a higher dosage of clarithromycin or alternative antibiotics based on sensitivity tests. Conclusions: We recommend at least 3 months of treatment with clarithromycin for treating skin infections caused by M. abscessus, with supplementary antibiotics selected based on patients' drug sensitivity tests.
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U2 - 10.1111/j.1365-4632.2005.02241.x
DO - 10.1111/j.1365-4632.2005.02241.x
M3 - Review article
C2 - 16207187
AN - SCOPUS:27544487517
SN - 0011-9059
VL - 44
SP - 846
EP - 850
JO - International Journal of Dermatology
JF - International Journal of Dermatology
IS - 10
ER -