Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence

Na Young Park; Jeong Hyun Lee; Myung Won Kim; Hee Gon Jeong; Byung Cheol Lee; Tae Sung Kim; Sang Ho Choi

doi:10.1128/IAI.74.1.721-728.2006

Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence

Na Young Park, Jeong Hyun Lee, Myung Won Kim, Hee Gon Jeong, Byung Cheol Lee, Tae Sung Kim, Sang Ho Choi

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

A wbpP gene encoding a putative UDP-N-acetyl-D-glucosamine C₄ epimerase was identified and cloned from Vibrio vulnificus. The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus.

Original language	English
Pages (from-to)	721-728
Number of pages	8
Journal	Infection and Immunity
Volume	74
Issue number	1
DOIs	https://doi.org/10.1128/IAI.74.1.721-728.2006
Publication status	Published - 2006 Jan

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/IAI.74.1.721-728.2006

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abstract = "A wbpP gene encoding a putative UDP-N-acetyl-D-glucosamine C4 epimerase was identified and cloned from Vibrio vulnificus. The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus.",

author = "Park, {Na Young} and Lee, {Jeong Hyun} and Kim, {Myung Won} and Jeong, {Hee Gon} and Lee, {Byung Cheol} and Kim, {Tae Sung} and Choi, {Sang Ho}",

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AU - Park, Na Young

AU - Lee, Jeong Hyun

AU - Kim, Myung Won

AU - Jeong, Hee Gon

AU - Lee, Byung Cheol

AU - Kim, Tae Sung

AU - Choi, Sang Ho

PY - 2006/1

Y1 - 2006/1

N2 - A wbpP gene encoding a putative UDP-N-acetyl-D-glucosamine C4 epimerase was identified and cloned from Vibrio vulnificus. The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus.

AB - A wbpP gene encoding a putative UDP-N-acetyl-D-glucosamine C4 epimerase was identified and cloned from Vibrio vulnificus. The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus.

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DO - 10.1128/IAI.74.1.721-728.2006

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Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence

Abstract

ASJC Scopus subject areas

UN SDGs

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