Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence

Na Young Park, Jeong Hyun Lee, Myung Won Kim, Hee Gon Jeong, Byung Cheol Lee, Tae Sung Kim, Sang Ho Choi

    Research output: Contribution to journalArticlepeer-review

    27 Citations (Scopus)

    Abstract

    A wbpP gene encoding a putative UDP-N-acetyl-D-glucosamine C4 epimerase was identified and cloned from Vibrio vulnificus. The functions of the wbpP gene, assessed by the construction of an isogenic mutant and by evaluating its phenotype changes, demonstrated that WbpP is essential in both the pathogenesis and the capsular polysaccharide biosynthesis of V. vulnificus.

    Original languageEnglish
    Pages (from-to)721-728
    Number of pages8
    JournalInfection and Immunity
    Volume74
    Issue number1
    DOIs
    Publication statusPublished - 2006 Jan

    ASJC Scopus subject areas

    • Parasitology
    • Microbiology
    • Immunology
    • Infectious Diseases

    Fingerprint

    Dive into the research topics of 'Identification of the Vibrio vulnificus wbpP gene and evaluation of its role in virulence'. Together they form a unique fingerprint.

    Cite this