Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data

Keyphrases

• In Cancer 100%
• Cancer Cells 100%
• High-throughput Screening 100%
• Kinase Inhibition 100%
• Kinase Dependency 100%
• Addiction 50%
• Ranker 50%
• Lung Cancer Cell Lines 33%
• Gene Expression 16%
• Cancer Treatment 16%
• Gene mutation 16%
• Data Expression 16%
• Screening Data 16%
• Patient Samples 16%
• Gene Expression Profile 16%
• Leukemia Patients 16%
• Mutation Status 16%
• Patient Cells 16%
• Ponatinib 16%
• Multikinase Inhibitor 16%
• Drug Polypharmacology 16%
• AZD8055 16%
• High-throughput Drug Screen 16%
• Synergistic Reduction 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Phosphotransferase 100%
• Drug Screening 100%
• Lung Cancer 18%
• Phosphotransferase Inhibitor 9%
• Leukemia 9%
• Ponatinib 9%
• Azd 8055 9%