Immunomodulatory and antigenotoxic properties of Bacillus amyloliquefaciens KU801

Na Kyoung Lee; So Yeon Kim; Hyo Ihl Chang; Eunju Park; Hyun Dong Paik

doi:10.4014/kjmb.1301.01008

Immunomodulatory and antigenotoxic properties of Bacillus amyloliquefaciens KU801

Na Kyoung Lee, So Yeon Kim, Hyo Ihl Chang, Eunju Park, Hyun Dong Paik

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The Bacillus KU801 strain, due to its potential in the field of probiotics for animal use, was isolated from chicken feces. Strain KU801 was identified as Bacillus amyloliquefaciens KU801 based on the results of 16S rRNA sequencing. Vegetative and spore cells of S. amyloliquefaciens KU801 were resistant to artificial gastric juice and artificial bile acid. B. amyloliquefaciens KU801 was found to inhibit the production of nitric oxide (NO) and increase the production of Interleukin-1 alpha (IL-Iα). DNA damage induced by N-methyl-Ntion of ninitroso-guanidine (MNNG) was significantly inhibited, in a dose dependent manner, by preincubating MNNG together with B. amyloliquefaciens KU801. These results demonstrate the potential use of B. amyloliquefaciens KU801 as a feed additive.

Original language	English
Pages (from-to)	249-252
Number of pages	4
Journal	Korean Journal of Microbiology and Biotechnology
Volume	41
Issue number	2
DOIs	https://doi.org/10.4014/kjmb.1301.01008
Publication status	Published - 2013 Jun

Keywords

DNA damage
Identification
Irieukin-1α
Nitritic oxide
Probiotic

ASJC Scopus subject areas

Biotechnology
Microbiology
Applied Microbiology and Biotechnology

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10.4014/kjmb.1301.01008

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title = "Immunomodulatory and antigenotoxic properties of Bacillus amyloliquefaciens KU801",

abstract = "The Bacillus KU801 strain, due to its potential in the field of probiotics for animal use, was isolated from chicken feces. Strain KU801 was identified as Bacillus amyloliquefaciens KU801 based on the results of 16S rRNA sequencing. Vegetative and spore cells of S. amyloliquefaciens KU801 were resistant to artificial gastric juice and artificial bile acid. B. amyloliquefaciens KU801 was found to inhibit the production of nitric oxide (NO) and increase the production of Interleukin-1 alpha (IL-Iα). DNA damage induced by N-methyl-Ntion of ninitroso-guanidine (MNNG) was significantly inhibited, in a dose dependent manner, by preincubating MNNG together with B. amyloliquefaciens KU801. These results demonstrate the potential use of B. amyloliquefaciens KU801 as a feed additive.",

keywords = "DNA damage, Identification, Irieukin-1α, Nitritic oxide, Probiotic",

author = "Lee, {Na Kyoung} and Kim, {So Yeon} and Chang, {Hyo Ihl} and Eunju Park and Paik, {Hyun Dong}",

year = "2013",

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doi = "10.4014/kjmb.1301.01008",

language = "English",

volume = "41",

pages = "249--252",

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AU - Lee, Na Kyoung

AU - Kim, So Yeon

AU - Chang, Hyo Ihl

AU - Park, Eunju

AU - Paik, Hyun Dong

PY - 2013/6

Y1 - 2013/6

N2 - The Bacillus KU801 strain, due to its potential in the field of probiotics for animal use, was isolated from chicken feces. Strain KU801 was identified as Bacillus amyloliquefaciens KU801 based on the results of 16S rRNA sequencing. Vegetative and spore cells of S. amyloliquefaciens KU801 were resistant to artificial gastric juice and artificial bile acid. B. amyloliquefaciens KU801 was found to inhibit the production of nitric oxide (NO) and increase the production of Interleukin-1 alpha (IL-Iα). DNA damage induced by N-methyl-Ntion of ninitroso-guanidine (MNNG) was significantly inhibited, in a dose dependent manner, by preincubating MNNG together with B. amyloliquefaciens KU801. These results demonstrate the potential use of B. amyloliquefaciens KU801 as a feed additive.

AB - The Bacillus KU801 strain, due to its potential in the field of probiotics for animal use, was isolated from chicken feces. Strain KU801 was identified as Bacillus amyloliquefaciens KU801 based on the results of 16S rRNA sequencing. Vegetative and spore cells of S. amyloliquefaciens KU801 were resistant to artificial gastric juice and artificial bile acid. B. amyloliquefaciens KU801 was found to inhibit the production of nitric oxide (NO) and increase the production of Interleukin-1 alpha (IL-Iα). DNA damage induced by N-methyl-Ntion of ninitroso-guanidine (MNNG) was significantly inhibited, in a dose dependent manner, by preincubating MNNG together with B. amyloliquefaciens KU801. These results demonstrate the potential use of B. amyloliquefaciens KU801 as a feed additive.

KW - DNA damage

KW - Identification

KW - Irieukin-1α

KW - Nitritic oxide

KW - Probiotic

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JF - Korean Journal of Microbiology and Biotechnology

IS - 2

ER -

Immunomodulatory and antigenotoxic properties of Bacillus amyloliquefaciens KU801

Abstract

Keywords

ASJC Scopus subject areas

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