Impact of Conjugated Linoleic Acid (CLA) on Skeletal Muscle Metabolism

Yoo Kim, Jonggun Kim, Kwang Youn Whang, Yeonhwa Park

    Research output: Contribution to journalReview articlepeer-review

    35 Citations (Scopus)

    Abstract

    Conjugated linoleic acid (CLA) has garnered special attention as a food bioactive compound that prevents and attenuates obesity. Although most studies on the effects of CLA on obesity have focused on the reduction of body fat, a number of studies have demonstrated that CLA also increases lean body mass and enhances physical performances. It has been suggested that these effects may be due in part to physiological changes in the skeletal muscle, such as changes in the muscle fiber type transformation, alteration of the intracellular signaling pathways in muscle metabolism, or energy metabolism. However, the mode of action for CLA in muscle metabolism is not completely understood. The purpose of this review is to summarize the current knowledge of the effects of CLA on skeletal muscle metabolism. Given that CLA not only reduces body fat, but also improves lean mass, there is great potential for the use of CLA to improve muscle metabolism, which would have a significant health impact.

    Original languageEnglish
    Pages (from-to)159-178
    Number of pages20
    JournalLipids
    Volume51
    Issue number2
    DOIs
    Publication statusPublished - 2016 Feb 1

    Bibliographical note

    Publisher Copyright:
    © 2016 AOCS.

    Copyright:
    Copyright 2017 Elsevier B.V., All rights reserved.

    Keywords

    • CLA
    • Conjugated linoleic acid
    • Lean body mass
    • Obesity
    • Physical activity
    • Skeletal muscle metabolism

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Cell Biology

    Fingerprint

    Dive into the research topics of 'Impact of Conjugated Linoleic Acid (CLA) on Skeletal Muscle Metabolism'. Together they form a unique fingerprint.

    Cite this