Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction

Nam Sik Yoon; Myung Ho Jeong; Youngkeun Ahn; Jong Hyun Kim; Shung Chull Chae; Young Jo Kim; Seung Ho Hur; In Whan Seong; Taek Jong Hong; Donghoon Choi; Myeong Chan Cho; Chong Jin Kim; Ki Bae Seung; Wook Sung Chung; Yang Soo Jang; Jeong Gwan Cho; Seung Jung Park; Bon Kwon Koo; Byung Ok Kim; Chong Yun Rhim; Dong Kyu Un; Doo Il Kim; Hyeon Cheol Gwon; In Ho Chae; Jae Young Rhew; Jang Ho Bae; Jei Keon Chae; Un Man Cho; Jin Yong Hwang; Jong Seon Park; Jung Han Yoon; Ju Young Yang; Kee Sik Kim; Keum Soo Park; Kyoo Rok Han; Kyoung Tae Jeong; Moo Hyun Kim; Myoung Yong Lee; Nae Hee Lee; Seok Kyu Oh; Seong Wook Park; Seong Woon Rha; Seung Jae Joo; Seung Jea Tahk; Soo Joong Kim; Tae Hoon Ahn; Young Youp Koh

doi:10.4070/kcj.2012.42.5.304

Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction

Nam Sik Yoon, Myung Ho Jeong, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Myeong Chan Cho, Chong Jin Kim, Ki Bae Seung, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Seung Jung Park, Bon Kwon Koo, Byung Ok Kim, Chong Yun RhimDong Kyu Un, Doo Il Kim, Hyeon Cheol Gwon, In Ho Chae, Jae Young Rhew, Jang Ho Bae, Jei Keon Chae, Un Man Cho, Jin Yong Hwang, Jong Seon Park, Jung Han Yoon, Ju Young Yang, Kee Sik Kim, Keum Soo Park, Kyoo Rok Han, Kyoung Tae Jeong, Moo Hyun Kim, Myoung Yong Lee, Nae Hee Lee, Seok Kyu Oh, Seong Wook Park, Seong Woon Rha, Seung Jae Joo, Seung Jea Tahk, Soo Joong Kim, Tae Hoon Ahn, Young Youp Koh

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Background and Objectives: Prehypertension according to JNC7 is common and is associated with increased vascular mortality. The importance of management in high-normal blood pressure (BP) is underemphasized. Subjects and Methods: We analyzed major adverse cardiac events (MACEs) in the Korea Acute Myocardial Infarction Registry in normal BP (group I) and high-normal BP (group II) patients. Results: Among 14871 patients, 159 (61±12.3 years, 122 males) satisfied the study indication. Six-month and one-year clinical follow-up rate was 88.9% and 85.8%, respectively. Group I had 78 patients (60.9±12.4 years). Group II had 81 patients (61.6±12.5 years). Demographics of patients were not different between groups. Treatment strategy was not different. Initial Thrombolysis in Myocardial Infarction flow grade 0 was less frequent in group II (n=32, 47.1%) than in group I (n=16, 21.9%) (p=0.001). Successful intervention rate was not different between group II (93.8%) and group I (97.1%) (p=0.590). Six-month MACE occurred in 3 patients in group I (4.4%) and 10 in group II (15.6%) (p=0.031). Compared with normal BP, the odds ratio for patients with high-normal BP was 1.147 (p=0.045, 95% confidence interval 1.011-1.402) for 6-month MACE. Conclusion: Even though high-normal BP patients had a better baseline clinical status, the prognosis was poorer than patients with normal BP. Therapeutic BP target goal for the patients with acute myocardial infarction should be < 140/90 mm Hg, which is recommended in JNC7.

Original language	English
Pages (from-to)	304-310
Number of pages	7
Journal	Korean Circulation Journal
Volume	42
Issue number	5
DOIs	https://doi.org/10.4070/kcj.2012.42.5.304
Publication status	Published - 2012 May

Keywords

Blood pressure
Prognosis

ASJC Scopus subject areas

Internal Medicine
Cardiology and Cardiovascular Medicine

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10.4070/kcj.2012.42.5.304

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Yoon, N. S., Jeong, M. H., Ahn, Y., Kim, J. H., Chae, S. C., Kim, Y. J., Hur, S. H., Seong, I. W., Hong, T. J., Choi, D., Cho, M. C., Kim, C. J., Seung, K. B., Chung, W. S., Jang, Y. S., Cho, J. G., Park, S. J., Koo, B. K., Kim, B. O., ... Koh, Y. Y. (2012). Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction. Korean Circulation Journal, 42(5), 304-310. https://doi.org/10.4070/kcj.2012.42.5.304

Yoon, NS, Jeong, MH, Ahn, Y, Kim, JH, Chae, SC, Kim, YJ, Hur, SH, Seong, IW, Hong, TJ, Choi, D, Cho, MC, Kim, CJ, Seung, KB, Chung, WS, Jang, YS, Cho, JG, Park, SJ, Koo, BK, Kim, BO, Rhim, CY, Un, DK, Kim, DI, Gwon, HC, Chae, IH, Rhew, JY, Bae, JH, Chae, JK, Cho, UM, Hwang, JY, Park, JS, Yoon, JH, Yang, JY, Kim, KS, Park, KS, Han, KR, Jeong, KT, Kim, MH, Lee, MY, Lee, NH, Oh, SK, Park, SW, Rha, SW, Joo, SJ, Tahk, SJ, Kim, SJ, Ahn, TH & Koh, YY 2012, 'Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction', Korean Circulation Journal, vol. 42, no. 5, pp. 304-310. https://doi.org/10.4070/kcj.2012.42.5.304

@article{c913c93c1d52411685121bb51910cfb1,

title = "Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction",

abstract = "Background and Objectives: Prehypertension according to JNC7 is common and is associated with increased vascular mortality. The importance of management in high-normal blood pressure (BP) is underemphasized. Subjects and Methods: We analyzed major adverse cardiac events (MACEs) in the Korea Acute Myocardial Infarction Registry in normal BP (group I) and high-normal BP (group II) patients. Results: Among 14871 patients, 159 (61±12.3 years, 122 males) satisfied the study indication. Six-month and one-year clinical follow-up rate was 88.9% and 85.8%, respectively. Group I had 78 patients (60.9±12.4 years). Group II had 81 patients (61.6±12.5 years). Demographics of patients were not different between groups. Treatment strategy was not different. Initial Thrombolysis in Myocardial Infarction flow grade 0 was less frequent in group II (n=32, 47.1%) than in group I (n=16, 21.9%) (p=0.001). Successful intervention rate was not different between group II (93.8%) and group I (97.1%) (p=0.590). Six-month MACE occurred in 3 patients in group I (4.4%) and 10 in group II (15.6%) (p=0.031). Compared with normal BP, the odds ratio for patients with high-normal BP was 1.147 (p=0.045, 95% confidence interval 1.011-1.402) for 6-month MACE. Conclusion: Even though high-normal BP patients had a better baseline clinical status, the prognosis was poorer than patients with normal BP. Therapeutic BP target goal for the patients with acute myocardial infarction should be < 140/90 mm Hg, which is recommended in JNC7.",

keywords = "Blood pressure, Prognosis",

author = "Yoon, {Nam Sik} and Jeong, {Myung Ho} and Youngkeun Ahn and Kim, {Jong Hyun} and Chae, {Shung Chull} and Kim, {Young Jo} and Hur, {Seung Ho} and Seong, {In Whan} and Hong, {Taek Jong} and Donghoon Choi and Cho, {Myeong Chan} and Kim, {Chong Jin} and Seung, {Ki Bae} and Chung, {Wook Sung} and Jang, {Yang Soo} and Cho, {Jeong Gwan} and Park, {Seung Jung} and Koo, {Bon Kwon} and Kim, {Byung Ok} and Rhim, {Chong Yun} and Un, {Dong Kyu} and Kim, {Doo Il} and Gwon, {Hyeon Cheol} and Chae, {In Ho} and Rhew, {Jae Young} and Bae, {Jang Ho} and Chae, {Jei Keon} and Cho, {Un Man} and Hwang, {Jin Yong} and Park, {Jong Seon} and Yoon, {Jung Han} and Yang, {Ju Young} and Kim, {Kee Sik} and Park, {Keum Soo} and Han, {Kyoo Rok} and Jeong, {Kyoung Tae} and Kim, {Moo Hyun} and Lee, {Myoung Yong} and Lee, {Nae Hee} and Oh, {Seok Kyu} and Park, {Seong Wook} and Rha, {Seong Woon} and Joo, {Seung Jae} and Tahk, {Seung Jea} and Kim, {Soo Joong} and Ahn, {Tae Hoon} and Koh, {Young Youp}",

year = "2012",

month = may,

doi = "10.4070/kcj.2012.42.5.304",

language = "English",

volume = "42",

pages = "304--310",

journal = "Korean Circulation Journal",

issn = "1738-5520",

publisher = "Korean Society of Cardiology",

number = "5",

}

TY - JOUR

T1 - Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction

AU - Yoon, Nam Sik

AU - Jeong, Myung Ho

AU - Ahn, Youngkeun

AU - Kim, Jong Hyun

AU - Chae, Shung Chull

AU - Kim, Young Jo

AU - Hur, Seung Ho

AU - Seong, In Whan

AU - Hong, Taek Jong

AU - Choi, Donghoon

AU - Cho, Myeong Chan

AU - Kim, Chong Jin

AU - Seung, Ki Bae

AU - Chung, Wook Sung

AU - Jang, Yang Soo

AU - Cho, Jeong Gwan

AU - Park, Seung Jung

AU - Koo, Bon Kwon

AU - Kim, Byung Ok

AU - Rhim, Chong Yun

AU - Un, Dong Kyu

AU - Kim, Doo Il

AU - Gwon, Hyeon Cheol

AU - Chae, In Ho

AU - Rhew, Jae Young

AU - Bae, Jang Ho

AU - Chae, Jei Keon

AU - Cho, Un Man

AU - Hwang, Jin Yong

AU - Park, Jong Seon

AU - Yoon, Jung Han

AU - Yang, Ju Young

AU - Kim, Kee Sik

AU - Park, Keum Soo

AU - Han, Kyoo Rok

AU - Jeong, Kyoung Tae

AU - Kim, Moo Hyun

AU - Lee, Myoung Yong

AU - Lee, Nae Hee

AU - Oh, Seok Kyu

AU - Park, Seong Wook

AU - Rha, Seong Woon

AU - Joo, Seung Jae

AU - Tahk, Seung Jea

AU - Kim, Soo Joong

AU - Ahn, Tae Hoon

AU - Koh, Young Youp

PY - 2012/5

Y1 - 2012/5

N2 - Background and Objectives: Prehypertension according to JNC7 is common and is associated with increased vascular mortality. The importance of management in high-normal blood pressure (BP) is underemphasized. Subjects and Methods: We analyzed major adverse cardiac events (MACEs) in the Korea Acute Myocardial Infarction Registry in normal BP (group I) and high-normal BP (group II) patients. Results: Among 14871 patients, 159 (61±12.3 years, 122 males) satisfied the study indication. Six-month and one-year clinical follow-up rate was 88.9% and 85.8%, respectively. Group I had 78 patients (60.9±12.4 years). Group II had 81 patients (61.6±12.5 years). Demographics of patients were not different between groups. Treatment strategy was not different. Initial Thrombolysis in Myocardial Infarction flow grade 0 was less frequent in group II (n=32, 47.1%) than in group I (n=16, 21.9%) (p=0.001). Successful intervention rate was not different between group II (93.8%) and group I (97.1%) (p=0.590). Six-month MACE occurred in 3 patients in group I (4.4%) and 10 in group II (15.6%) (p=0.031). Compared with normal BP, the odds ratio for patients with high-normal BP was 1.147 (p=0.045, 95% confidence interval 1.011-1.402) for 6-month MACE. Conclusion: Even though high-normal BP patients had a better baseline clinical status, the prognosis was poorer than patients with normal BP. Therapeutic BP target goal for the patients with acute myocardial infarction should be < 140/90 mm Hg, which is recommended in JNC7.

AB - Background and Objectives: Prehypertension according to JNC7 is common and is associated with increased vascular mortality. The importance of management in high-normal blood pressure (BP) is underemphasized. Subjects and Methods: We analyzed major adverse cardiac events (MACEs) in the Korea Acute Myocardial Infarction Registry in normal BP (group I) and high-normal BP (group II) patients. Results: Among 14871 patients, 159 (61±12.3 years, 122 males) satisfied the study indication. Six-month and one-year clinical follow-up rate was 88.9% and 85.8%, respectively. Group I had 78 patients (60.9±12.4 years). Group II had 81 patients (61.6±12.5 years). Demographics of patients were not different between groups. Treatment strategy was not different. Initial Thrombolysis in Myocardial Infarction flow grade 0 was less frequent in group II (n=32, 47.1%) than in group I (n=16, 21.9%) (p=0.001). Successful intervention rate was not different between group II (93.8%) and group I (97.1%) (p=0.590). Six-month MACE occurred in 3 patients in group I (4.4%) and 10 in group II (15.6%) (p=0.031). Compared with normal BP, the odds ratio for patients with high-normal BP was 1.147 (p=0.045, 95% confidence interval 1.011-1.402) for 6-month MACE. Conclusion: Even though high-normal BP patients had a better baseline clinical status, the prognosis was poorer than patients with normal BP. Therapeutic BP target goal for the patients with acute myocardial infarction should be < 140/90 mm Hg, which is recommended in JNC7.

KW - Blood pressure

KW - Prognosis

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U2 - 10.4070/kcj.2012.42.5.304

DO - 10.4070/kcj.2012.42.5.304

M3 - Article

C2 - 22701132

AN - SCOPUS:84862577920

SN - 1738-5520

VL - 42

SP - 304

EP - 310

JO - Korean Circulation Journal

JF - Korean Circulation Journal

IS - 5

ER -

Impact of high-normal blood pressure measured in emergency room on adverse cardiac events in acute myocardial infarction

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