Implementation of a biocircuit implants for neurotransmitter release during neuro-stimulation

Suw Young Ly, Dal Woong Choi

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    Neurotransmitter assay of epinephrine (EP) was sought using a modified carbon nanotube paste electrode (PE). Using optimum conditions, cyclic voltammetry (CV) and the square wave (SW) stripping voltammetric working ranges were attained to 10-100 mgL-1 (CV) and 20-140 ngL-1 (SW). The relative standard deviation of 0.0549 (n=15) was obtained at 20.0 mgL -1 EP constant. Here, the analytical detection limit (S/N) was reached with 4.60 ngL-1 (2.5×10-11 molL-1) EP. The hand-made electrode was implanted into the in-vivo brain core of the animals and was used in chronoamperometric neuro detection. The results obtained are applicable in neuro sensing, physiological control, and other neuroscience fields.

    Original languageEnglish
    Pages (from-to)238-246
    Number of pages9
    JournalCurrent Neurovascular Research
    Volume10
    Issue number3
    DOIs
    Publication statusPublished - 2013 Aug

    Keywords

    • Brain
    • Electrochemical
    • Epinephrine
    • In vivo
    • Interface
    • Neuro sens

    ASJC Scopus subject areas

    • Neurology
    • Developmental Neuroscience
    • Cellular and Molecular Neuroscience

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