Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces

Ji Hun Seo; Sachiro Kakinoki; Yuuki Inoue; Tetsuji Yamaoka; Kazuhiko Ishihara; Nobuhiko Yui

doi:10.1021/ja400817q

Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces

Ji Hun Seo
, Sachiro Kakinoki
, Yuuki Inoue
, Tetsuji Yamaoka
, Kazuhiko Ishihara
, Nobuhiko Yui^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

110 Citations (Scopus)

Abstract

The rapid response of integrin β₁ molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material-cell interactions.

Original language	English
Pages (from-to)	5513-5516
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	135
Issue number	15
DOIs	https://doi.org/10.1021/ja400817q
Publication status	Published - 2013 Apr 17
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja400817q

Cite this

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title = "Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces",

abstract = "The rapid response of integrin β1 molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material-cell interactions.",

author = "Seo, \{Ji Hun\} and Sachiro Kakinoki and Yuuki Inoue and Tetsuji Yamaoka and Kazuhiko Ishihara and Nobuhiko Yui",

year = "2013",

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doi = "10.1021/ja400817q",

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AU - Seo, Ji Hun

AU - Kakinoki, Sachiro

AU - Inoue, Yuuki

AU - Yamaoka, Tetsuji

AU - Ishihara, Kazuhiko

AU - Yui, Nobuhiko

PY - 2013/4/17

Y1 - 2013/4/17

N2 - The rapid response of integrin β1 molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material-cell interactions.

AB - The rapid response of integrin β1 molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material-cell interactions.

UR - https://www.scopus.com/pages/publications/84876472350

U2 - 10.1021/ja400817q

DO - 10.1021/ja400817q

M3 - Article

C2 - 23544620

AN - SCOPUS:84876472350

SN - 0002-7863

VL - 135

SP - 5513

EP - 5516

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 15

ER -

Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces

Abstract

ASJC Scopus subject areas

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