Influence of bottle-feeding on serum bisphenol a levels in infants

Young Jun Rhie, Hyo Kyoung Nam, Yeon Joung Oh, Ho Seong Kim, Kee Hyoung Lee

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Exposure to endocrine disrupting chemicals (EDCs), particularly during developmental periods, gives rise to a variety of adverse health outcomes. Bisphenol A (BPA) is a well-known EDC commonly found in plastic products including food and water containers, baby bottles, and metal can linings. This study investigates infant exposure to BPA and the effect of bottle-feeding on serum BPA levels in infants. Serum BPA levels in normal healthy infants 6 to 15 months of age (n=60) were evaluated by a competitive ELISA. BPA was detected in every study sample. Serum BPA levels of bottle-fed infants (n=30) were significantly higher than those of breast-fed infants (n=30) (96.58±102.36 vs 45.53±34.05 pg/mL, P=0.014). There were no significant differences in serum BPA levels between boys (n=31) and girls (n=29). No significant correlations were found between serum BPA levels and age, body weight, birth weight, and gestational age. Bottle-feeding seems to increase the risk of infant exposure to BPA. Establishment of health policies to reduce or prevent BPA exposure in infants is necessary.

Original languageEnglish
Pages (from-to)261-264
Number of pages4
JournalJournal of Korean medical science
Issue number2
Publication statusPublished - 2014

Bibliographical note

Publisher Copyright:
© 2014 The Korean Academy of Medical Sciences.


  • Baby bottle
  • Bisphenol A
  • Bottle-Feeding
  • Endocrine disrupting chemical
  • Infant

ASJC Scopus subject areas

  • General Medicine


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