Influence of smartphone Wi-Fi signals on adipose-derived stem cells

Sang Soon Lee, Hyung Rok Kim, Min Sook Kim, Sanghoon Park, Eul Sik Yoon, Seung Ha Park, Deok Woo Kim

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)


    The use of smartphones is expanding rapidly around the world, thus raising the concern of possible harmful effects of radiofrequency generated by smartphones. We hypothesized that Wi-Fi signals from smartphones may have harmful influence on adiposederived stem cells (ASCs). An in vitro study was performed to assess the influence of Wi-Fi signals from smartphones. The ASCs were incubated under a smartphone connected to a Wi-Fi network, which was uploading files at a speed of 4.8 Mbps for 10 hours a day, for a total of 5 days. We constructed 2 kinds of control cells, one grown in 37°C and the other grown in 39°C. After 5 days of Wi-Fi exposure from the smartphone, the cells underwent cell proliferation assay, apoptosis assay, and flow cytometry analysis. Three growth factors, vascular endothelial growth factor, hepatocyte growth factor, and transforming growth factor-β, were measured from ASC-conditioned media. Cell proliferation rate was higher in Wi-Fi-exposed cells and 39°C control cells compared with 37°C control cells. Apoptosis assay, flow cytometry analysis, and growth factor concentrations showed no remarkable differences among the 3 groups. We could not find any harmful effects of Wi-Fi electromagnetic signals from smartphones. The increased proliferation of ASCs under the smartphone, however, might be attributable to the thermal effect.

    Original languageEnglish
    Pages (from-to)1902-1907
    Number of pages6
    JournalJournal of Craniofacial Surgery
    Issue number5
    Publication statusPublished - 2014

    Bibliographical note

    Publisher Copyright:
    Copyright © 2014 by Mutaz B. Habal, MD.


    • Adipose-derived stem cell
    • Apoptosis
    • Electromagnetic
    • Growth factor
    • Proliferation
    • Smartphone
    • Wi-Fi

    ASJC Scopus subject areas

    • Surgery
    • Otorhinolaryngology


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