Abstract
Influenza is a worldwide public health concern. Since the introduction of trivalent influenza vaccine in 1978, vaccination has been the primary means of prevention and control of influenza. Current influenza vaccines have moderate efficacy, good safety, and acceptable tolerability; however, they have unsatisfactory efficacy in older adults, are dependent on egg supply for production, and are time-consuming to manufacture. This review outlines the unmet medical needs of current influenza vaccines. Recent developments in influenza vaccines are also described.
Original language | English |
---|---|
Pages (from-to) | 375-386 |
Number of pages | 12 |
Journal | Infection and Chemotherapy |
Volume | 45 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2013 Dec |
Externally published | Yes |
Keywords
- Human
- Influenza
- Influenza vaccines
- Pandemics
ASJC Scopus subject areas
- Infectious Diseases
- Pharmacology (medical)