Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients

Jong Su Park; Su Jin Kim; Sung Woo Lee; Eui Jung Lee; Kap Su Han; Sung Woo Moon; Yun Sik Hong

doi:10.1016/j.jemermed.2015.02.038

Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients

Jong Su Park, Su Jin Kim, Sung Woo Lee, Eui Jung Lee, Kap Su Han, Sung Woo Moon, Yun Sik Hong

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Background In severe sepsis and septic shock, global tissue hypoxia is a key development preceding multi-organ failure and death. Objective Our aim was to find whether the initial low oxygen extraction ratio (OER) is related to the severity of organ dysfunction and to predict the in-hospital mortality in severe sepsis or septic shock patients. Methods This was a secondary analysis of 169 patients with severe sepsis or septic shock in an emergency department. We calculated OER with 1- central venous oxygen saturation (ScvO₂)/arterial oxygen saturation and compared the data according to the level of OER (high > 0.3, 0.2).

Original language	English
Pages (from-to)	261-267
Number of pages	7
Journal	Journal of Emergency Medicine
Volume	49
Issue number	3
DOIs	https://doi.org/10.1016/j.jemermed.2015.02.038
Publication status	Published - 2015 Sept 1

Keywords

central venous oxygen saturation
mortality
organ dysfunction
oxygen extraction ratio
sepsis

ASJC Scopus subject areas

Emergency Medicine

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10.1016/j.jemermed.2015.02.038

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title = "Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients",

abstract = "Background In severe sepsis and septic shock, global tissue hypoxia is a key development preceding multi-organ failure and death. Objective Our aim was to find whether the initial low oxygen extraction ratio (OER) is related to the severity of organ dysfunction and to predict the in-hospital mortality in severe sepsis or septic shock patients. Methods This was a secondary analysis of 169 patients with severe sepsis or septic shock in an emergency department. We calculated OER with 1- central venous oxygen saturation (ScvO2)/arterial oxygen saturation and compared the data according to the level of OER (high > 0.3, 0.2).",

keywords = "central venous oxygen saturation, mortality, organ dysfunction, oxygen extraction ratio, sepsis",

author = "Park, {Jong Su} and Kim, {Su Jin} and Lee, {Sung Woo} and Lee, {Eui Jung} and Han, {Kap Su} and Moon, {Sung Woo} and Hong, {Yun Sik}",

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doi = "10.1016/j.jemermed.2015.02.038",

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T1 - Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients

AU - Park, Jong Su

AU - Kim, Su Jin

AU - Lee, Sung Woo

AU - Lee, Eui Jung

AU - Han, Kap Su

AU - Moon, Sung Woo

AU - Hong, Yun Sik

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Background In severe sepsis and septic shock, global tissue hypoxia is a key development preceding multi-organ failure and death. Objective Our aim was to find whether the initial low oxygen extraction ratio (OER) is related to the severity of organ dysfunction and to predict the in-hospital mortality in severe sepsis or septic shock patients. Methods This was a secondary analysis of 169 patients with severe sepsis or septic shock in an emergency department. We calculated OER with 1- central venous oxygen saturation (ScvO2)/arterial oxygen saturation and compared the data according to the level of OER (high > 0.3, 0.2).

AB - Background In severe sepsis and septic shock, global tissue hypoxia is a key development preceding multi-organ failure and death. Objective Our aim was to find whether the initial low oxygen extraction ratio (OER) is related to the severity of organ dysfunction and to predict the in-hospital mortality in severe sepsis or septic shock patients. Methods This was a secondary analysis of 169 patients with severe sepsis or septic shock in an emergency department. We calculated OER with 1- central venous oxygen saturation (ScvO2)/arterial oxygen saturation and compared the data according to the level of OER (high > 0.3, 0.2).

KW - central venous oxygen saturation

KW - mortality

KW - organ dysfunction

KW - oxygen extraction ratio

KW - sepsis

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Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients

Abstract

Keywords

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