@inproceedings{725ac68418e041808eafc907ca3d76a0,
title = "Integrated photonic structures for parallel fluorescence and refractive index biosensing",
abstract = "We present a multi-modality optical sensing platform employing integrated Vertical Cavity Surface Emitting Lasers (VCSELs), photodetectors, and filters suitable for portable, real-time analyte detection in aqueous environments. Fluorescence and refractive index sensors designed to utilize visible and near-infrared VCSELs for low background absorption from analyte delivery fluids are described. We demonstrate in vitro fluorescence sensing of Cy5.5 dye with a detection sensitivity of 5 nM and photonic crystal slab refractive index sensing with tunable GaAs-based 670 nm VCSELs. This compact, parallel sensor architecture enables multiplexed, cost-effective on-chip biosensing.",
keywords = "Biosensing, Fluorescence, Integrated, Lab-on-a-chip, Label free, Photonic crystal, Sensor, VCSEL",
author = "Lee, {Meredith M.} and O'Sullivan, {Thomas D.} and Antonio Cerruto and Victor Liu and Jingyu Zhang and Ofer Levi and Heon Lee and Brueck, {Steven R.J.} and Shanhui Fan and Harris, {James S.}",
year = "2011",
doi = "10.1117/12.884228",
language = "English",
isbn = "9780819486080",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
booktitle = "Photonic Microdevices/Microstructures for Sensing III",
note = "Photonic Microdevices/Microstructures for Sensing III ; Conference date: 27-04-2011 Through 28-04-2011",
}