Inter-fractional entrance dose monitoring as quality assurance using Gafchromic EBT3 film

Sun Young Moon, Yunhui Jo, Jaehyeon Seo, Dongho Shin, Myonggeun Yoon

Research output: Contribution to journalArticlepeer-review


Introduction: This study describes a simple method of inter-fractional photon beam monitoring to measure the entrance dose of radiation treatment using Gafchromic EBT3 film. Materials and Methods: The film was placed at the center of a 1-cm thick phantom shaped like a block tray and fixed on the accessory tray of the gantry. The entrance dose was measured following the placement of the film in the accessory tray. The dose distribution calculated with the treatment planning system was compared with the dose distribution on the irradiated EBT3 films. The effectiveness of this methodology, as determined by gamma passing rates, was evaluated for the 22 fields of eight three-dimensional conformal radiotherapy (3D-CRT) plans and the 41 fields of nine intensity-modulated radiotherapy (RT) plans. The plans for three-dimensional conformal RT included treatments of the rectum, liver, breast, and head and neck, whereas the plans for intensity-modulated RT included treatments of the liver, brain, and lung. Results: The gamma passing rates for 3D-CRT ranged from 96.4% to 99.5%, with the mean gamma passing rate for 22 fields being 98.0%. The gamma passing rate for intensity-modulated RT ranged from 96.1% to 98.9%, with the mean gamma passing rate for 41 fields being 97.7%. All gamma indices were over the 95% tolerance level. Conclusions: The methodology described in this study, based on Gafchromic EBT3 film, can be utilized for inter-fractional entrance dose monitoring as quality assurance during RT. Clinical application of this method to patients can verify the accuracy of beam delivery in the treatment room.

Original languageEnglish
Pages (from-to)1152-1158
Number of pages7
JournalJournal of Cancer Research and Therapeutics
Issue number4
Publication statusPublished - 2022 Jul 1

Bibliographical note

Funding Information:
This work was supported by the Basic Science Research Program through the National Research Foundation (NRF) of Korea, funded by the Ministry of Education (NRF‑2017R1D1A1B03031056 and NRF‑2018R1D1A1B07047770).

Publisher Copyright:
© 2022 Wolters Kluwer Medknow Publications. All rights reserved.


  • Gafchromic EBT3 film
  • Intensity-modulated radiotherapy
  • Inter-fractional dosimetry
  • Three-dimensional conformal radiotherapy
  • Treatment quality assurance

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging


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