Abstract
Touch, Pauson, engage: To explain the unique superior reactivity and stereoselectivity of O-tethered enynes in asymmetric Pauson-Khand type reaction (APKR) than their congeners, the internal-chelation to metal of oxygen atom of the substrate in the transition state was proposed. This proposition was well supported by APKR with several different substrates.
Original language | English |
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Pages (from-to) | 2009-2014 |
Number of pages | 6 |
Journal | Chemistry - An Asian Journal |
Volume | 6 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2011 Aug 1 |
Keywords
- Pauson-Khand reaction
- chelation effects
- enantioselectivity
- kinetic resolution
- rhodium
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry