Abstract
Background: This study aimed to estimate the population-attributable risks (PARs) of 9 major risk factors for stroke in Korea through a case-control study and to test the feasibility and validity of internet-based control recruitment. Methods: From April 2008 to September 2009 controls were enrolled via internet after providing consent for participation through a web-based survey. The cases included patients who were admitted to the participating centers due to acute stroke or transient ischemic attack within 7 days of onset during the study period. Each control was age- and sex-matched with 2 cases. Adjusted odd ratios, age-standardized prevalence, and PARs were estimated for the 9 major risk factors using the prevalence of risk factors in the control group and the age and sex characteristics from Korea's national census data. Results: In total, 1041 controls were matched to 2082 stroke cases. Because of a shortage of elderly controls in the internet-based recruitment, 248 controls were recruited off-line. The PARs were 23.44%, 10.95%, 51.32%, and 6.35% for hypertension, diabetes, smoking, and stroke history, respectively. Hypercholesterolemia, atrial fibrillation, obesity, coronary heart disease, and a family history of stroke were not associated with stroke. Comparison with education and religion of the control group with that mentioned in the national census data showed a notable difference. Conclusions: The study results imply that internet-based control recruitment for a case- control study requires careful selection of risk factors with high self-awareness and effective strategies to facilitate the recruitment of elderly participants.
Original language | English |
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Pages (from-to) | 2559-2565 |
Number of pages | 7 |
Journal | Journal of Stroke and Cerebrovascular Diseases |
Volume | 23 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |
Bibliographical note
Funding Information:This study was supported by a grant of the Korea Healthcare technology R&D Project , Ministry of Health and Welfare , Republic of Korea ( HI10C2020 ).
Publisher Copyright:
© 2014 by National Stroke Association.
Keywords
- Based study
- Case
- Control study
- Internet
- Risk factors
- Stroke
ASJC Scopus subject areas
- Surgery
- Rehabilitation
- Clinical Neurology
- Cardiology and Cardiovascular Medicine