Investigation of zwitterionic 7-ammonium-7,9-nido-m-carborane

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Abstract

Zwitterionic ammonium-substituted nido m-carborane (7-NH3-7,9-nido-carborane), a novel boron moiety for boron neutron capture therapy, was synthesized and its chemical properties were investigated. This boron cluster system showed unique properties by reacting with carbonyl groups of ketones and aldehydes to generate the corresponding iminium-substituted nido m-carboranes.

Original languageEnglish
Pages (from-to)5649-5652
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number32
DOIs
Publication statusPublished - 2006 Aug 7
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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