Is ridge preservation effective in the extraction sockets of periodontally compromised teeth? A randomized controlled trial

Heithem Ben Amara, Jung Ju Kim, Hae Young Kim, Jungwon Lee, Hyun Young Song, Ki Tae Koo

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Objective: To verify whether ridge preservation is effective in the reduction of dimensional loss and in bone formation compared to spontaneous healing in extraction sockets of periodontally compromised teeth. Methods: Twenty-six subjects requiring tooth extraction for stage III/IV periodontitis were randomly assigned to one of two interventions: alveolar ridge preservation using collagenated bovine bone mineral and a resorbable collagen membrane (test, RP) or spontaneous healing (control, SH). Six months later, postoperative cone-beam computed tomography (CBCT) was performed to measure the linear and volumetric changes of the sockets compared to baseline scans. Biopsies were retrieved at the implant site for histomorphometric calculations. Nonparametric tests were applied for statistical analysis. Results: Significantly less shrinkage occurred in RP compared to SH, mainly in the crestal zone. The width loss difference between groups was 3.3 mm and 2.2 mm at 1 mm and 3 mm below the crest, respectively (p <.05). RP yielded a gain in socket height of 0.25 mm, whereas a loss of −0.39 mm was observed in SH (p <.05). The percentage of volume loss recorded in RP was also less than that recorded in SH (−26.53% vs −50.34, p <.05). Significantly less bone proportion was detected in biopsies from RP (30.1%) compared with SH (53.9%). A positive association between baseline bone loss and ridge shrinkage was found in SH but not in RP. Conclusion: Ridge preservation in extraction sockets of periodontally compromised teeth was effective in reducing the amount of ridge resorption.

Original languageEnglish
Pages (from-to)464-477
Number of pages14
JournalJournal of Clinical Periodontology
Issue number3
Publication statusPublished - 2021 Mar

Bibliographical note

Funding Information:
This study was supported by a grant from Geistlich Pharma AG, Wolhusen, Switzerland. The funders had no role in study design, data collection, data analysis, decision to publish, or preparation of the paper.

Publisher Copyright:
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd


  • compromised socket
  • periodontitis
  • ridge dimension
  • ridge preservation
  • tooth extraction

ASJC Scopus subject areas

  • Periodontics


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