Abstract
Bioresorbable implantable medical devices can be employed in versatile clinical scenarios that burden patients with complications and surgical removal of conventional devices. However, a shortage of suitable electricalinterconnection materials limits the development of bioresorbable electronic systems. Therefore, this study highlights a highly conductive, naturally resorbable paste exhibiting enhanced electrical conductivity and mechanical stability that can solve the existing problems of bioresorbable interconnections. Multifaceted experiments on electrical and physical properties were used to optimize the composition of pastes containing beeswax, submicron tungstenparticles, and glycofurol. These pastes embody isotropic conductive paths for three-dimensional interconnects and function as antennas, sensors, and contact pads for bioresorbable electronic devices. The degradation behavior in aqueous solutions was used to assess its stability and ability to retain electrical conductance (∼7 kS/m) and structural form over the requisite dissolution period. In vitro and in vivo biocompatibility tests clarified the safety of the paste as an implantable material.
Original language | English |
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Article number | 100541 |
Journal | Materials Today Bio |
Volume | 18 |
DOIs | |
Publication status | Published - 2023 Feb |
Bibliographical note
Funding Information:H.L. acknowledges the support from the Korea government ( MSIT ) (No. NRF- 2021R1C1C1005050 ). K.L. granted by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute ( KHIDI ), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI22C1394 ). J.K. acknowledges the support from the Korea government ( MSIT ) (Grant No. NRF-2021R1A2C2094799 ), Korea Health Industry Development Institute (KHIDI) (Grant No. HI22C0647 ), and Korea University (Grant No. K2109981 ). This work was in part supported by the Research Institute for Convergence Science .
Publisher Copyright:
© 2023 The Authors
Keywords
- Biodegradable electronics
- Conductive paste
- Implantable medical device
- Isotropic conductive adhesive
- Screen printing
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomaterials
- Biomedical Engineering
- Molecular Biology
- Cell Biology