Korean frailty and aging cohort study (KFACS): Cohort profile

Chang Won Won; Seoyoon Lee; Jinhee Kim; Doukyoung Chon; Sunyoung Kim; Chang O. Kim; Mi Kyung Kim; Belong Cho; Kyung Mook Choi; Eun Roh; Hak Chul Jang; Sang Joon Son; Jin Hee Lee; Yong Soon Park; Sam Gyu Lee; Bong Jo Kim; Hyeon Ju Kim; Jaekyung Choi; Hyuk Ga; Kee Jae Lee; Yunhwan Lee; Miji Kim

doi:10.1136/bmjopen-2019-035573

Korean frailty and aging cohort study (KFACS): Cohort profile

Chang Won Won, Seoyoon Lee, Jinhee Kim, Doukyoung Chon, Sunyoung Kim, Chang O. Kim, Mi Kyung Kim, Belong Cho, Kyung Mook Choi, Eun Roh, Hak Chul Jang, Sang Joon Son, Jin Hee Lee, Yong Soon Park, Sam Gyu Lee, Bong Jo Kim, Hyeon Ju Kim, Jaekyung Choi, Hyuk Ga, Kee Jae LeeYunhwan Lee, Miji Kim

Research output: Contribution to journal › Article › peer-review

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Abstract

Purpose The purpose of the Korean Frailty and Aging Cohort Study (KFACS) is to initiate a nationwide, population-based prospective cohort study of older adults living in the community to assess their frailty status and explore transitions between frailty states over time in Korea. Participants The KFACS is a multicentre longitudinal study with the baseline survey conducted from May 2016 to November 2017. Each centre recruited participants using quota sampling stratified by age and sex. The number of participants recruited through 2 years of baseline study from 10 centres was 3014, with each site accounting for approximately 300 participants. The inclusion criteria were: having an age of 70-84 years, currently living in the community, having no plans to move out in the next 2 years, having no problems with communication and no prior dementia diagnosis. Findings to date To define physical frailty, the KFACS used a modified version of the Fried Frailty Phenotype (FFP) consisting of five components of frailty: unintended weight loss, weakness, self-reported exhaustion, slowness and low physical activity. In the baseline study of 2016-2017, 2907 of 3014 individuals fulfilled all five components of FFP. The results indicated that 7.8% of the participants (n=228) were frail, 47.0% (n=1366) were prefrail and 45.2% (n=1313) were robust. The prevalence of frailty increased with age in both sexes; in the group aged 70-74 years, 1.8% of men and 3.7% of women were frail, whereas in the 80-84 years age group, 14.9% of men and 16.7% of women were frail. Women tended to exhibit a higher prevalence of frailty than men in all age groups. Future plans The KFACS plans to identify outcomes and risk factors associated with frailty by conducting a 10-year cohort study, with a follow-up every 2 years, using 3014 baseline participants.

Original language	English
Article number	e035573
Journal	BMJ open
Volume	10
Issue number	4
DOIs	https://doi.org/10.1136/bmjopen-2019-035573
Publication status	Published - 2020 Apr 22

Bibliographical note

Funding Information:
Funding This research was supported by a grant from the Korea Health Technology R&D Project through the Korean Health Industry Development Institute, which is funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI15C3153).

Publisher Copyright:
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords

geriatric medicine
preventive medicine
public health

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/bmjopen-2019-035573

Cite this

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title = "Korean frailty and aging cohort study (KFACS): Cohort profile",

abstract = "Purpose The purpose of the Korean Frailty and Aging Cohort Study (KFACS) is to initiate a nationwide, population-based prospective cohort study of older adults living in the community to assess their frailty status and explore transitions between frailty states over time in Korea. Participants The KFACS is a multicentre longitudinal study with the baseline survey conducted from May 2016 to November 2017. Each centre recruited participants using quota sampling stratified by age and sex. The number of participants recruited through 2 years of baseline study from 10 centres was 3014, with each site accounting for approximately 300 participants. The inclusion criteria were: having an age of 70-84 years, currently living in the community, having no plans to move out in the next 2 years, having no problems with communication and no prior dementia diagnosis. Findings to date To define physical frailty, the KFACS used a modified version of the Fried Frailty Phenotype (FFP) consisting of five components of frailty: unintended weight loss, weakness, self-reported exhaustion, slowness and low physical activity. In the baseline study of 2016-2017, 2907 of 3014 individuals fulfilled all five components of FFP. The results indicated that 7.8% of the participants (n=228) were frail, 47.0% (n=1366) were prefrail and 45.2% (n=1313) were robust. The prevalence of frailty increased with age in both sexes; in the group aged 70-74 years, 1.8% of men and 3.7% of women were frail, whereas in the 80-84 years age group, 14.9% of men and 16.7% of women were frail. Women tended to exhibit a higher prevalence of frailty than men in all age groups. Future plans The KFACS plans to identify outcomes and risk factors associated with frailty by conducting a 10-year cohort study, with a follow-up every 2 years, using 3014 baseline participants.",

keywords = "geriatric medicine, preventive medicine, public health",

author = "Won, {Chang Won} and Seoyoon Lee and Jinhee Kim and Doukyoung Chon and Sunyoung Kim and Kim, {Chang O.} and Kim, {Mi Kyung} and Belong Cho and Choi, {Kyung Mook} and Eun Roh and Jang, {Hak Chul} and Son, {Sang Joon} and Lee, {Jin Hee} and Park, {Yong Soon} and Lee, {Sam Gyu} and Kim, {Bong Jo} and Kim, {Hyeon Ju} and Jaekyung Choi and Hyuk Ga and Lee, {Kee Jae} and Yunhwan Lee and Miji Kim",

note = "Funding Information: Funding This research was supported by a grant from the Korea Health Technology R&D Project through the Korean Health Industry Development Institute, which is funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI15C3153). Publisher Copyright: {\textcopyright} Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",

year = "2020",

month = apr,

day = "22",

doi = "10.1136/bmjopen-2019-035573",

language = "English",

volume = "10",

journal = "BMJ open",

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T1 - Korean frailty and aging cohort study (KFACS)

T2 - Cohort profile

AU - Won, Chang Won

AU - Lee, Seoyoon

AU - Kim, Jinhee

AU - Chon, Doukyoung

AU - Kim, Sunyoung

AU - Kim, Chang O.

AU - Kim, Mi Kyung

AU - Cho, Belong

AU - Choi, Kyung Mook

AU - Roh, Eun

AU - Jang, Hak Chul

AU - Son, Sang Joon

AU - Lee, Jin Hee

AU - Park, Yong Soon

AU - Lee, Sam Gyu

AU - Kim, Bong Jo

AU - Kim, Hyeon Ju

AU - Choi, Jaekyung

AU - Ga, Hyuk

AU - Lee, Kee Jae

AU - Lee, Yunhwan

AU - Kim, Miji

N1 - Funding Information: Funding This research was supported by a grant from the Korea Health Technology R&D Project through the Korean Health Industry Development Institute, which is funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI15C3153). Publisher Copyright: © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2020/4/22

Y1 - 2020/4/22

N2 - Purpose The purpose of the Korean Frailty and Aging Cohort Study (KFACS) is to initiate a nationwide, population-based prospective cohort study of older adults living in the community to assess their frailty status and explore transitions between frailty states over time in Korea. Participants The KFACS is a multicentre longitudinal study with the baseline survey conducted from May 2016 to November 2017. Each centre recruited participants using quota sampling stratified by age and sex. The number of participants recruited through 2 years of baseline study from 10 centres was 3014, with each site accounting for approximately 300 participants. The inclusion criteria were: having an age of 70-84 years, currently living in the community, having no plans to move out in the next 2 years, having no problems with communication and no prior dementia diagnosis. Findings to date To define physical frailty, the KFACS used a modified version of the Fried Frailty Phenotype (FFP) consisting of five components of frailty: unintended weight loss, weakness, self-reported exhaustion, slowness and low physical activity. In the baseline study of 2016-2017, 2907 of 3014 individuals fulfilled all five components of FFP. The results indicated that 7.8% of the participants (n=228) were frail, 47.0% (n=1366) were prefrail and 45.2% (n=1313) were robust. The prevalence of frailty increased with age in both sexes; in the group aged 70-74 years, 1.8% of men and 3.7% of women were frail, whereas in the 80-84 years age group, 14.9% of men and 16.7% of women were frail. Women tended to exhibit a higher prevalence of frailty than men in all age groups. Future plans The KFACS plans to identify outcomes and risk factors associated with frailty by conducting a 10-year cohort study, with a follow-up every 2 years, using 3014 baseline participants.

AB - Purpose The purpose of the Korean Frailty and Aging Cohort Study (KFACS) is to initiate a nationwide, population-based prospective cohort study of older adults living in the community to assess their frailty status and explore transitions between frailty states over time in Korea. Participants The KFACS is a multicentre longitudinal study with the baseline survey conducted from May 2016 to November 2017. Each centre recruited participants using quota sampling stratified by age and sex. The number of participants recruited through 2 years of baseline study from 10 centres was 3014, with each site accounting for approximately 300 participants. The inclusion criteria were: having an age of 70-84 years, currently living in the community, having no plans to move out in the next 2 years, having no problems with communication and no prior dementia diagnosis. Findings to date To define physical frailty, the KFACS used a modified version of the Fried Frailty Phenotype (FFP) consisting of five components of frailty: unintended weight loss, weakness, self-reported exhaustion, slowness and low physical activity. In the baseline study of 2016-2017, 2907 of 3014 individuals fulfilled all five components of FFP. The results indicated that 7.8% of the participants (n=228) were frail, 47.0% (n=1366) were prefrail and 45.2% (n=1313) were robust. The prevalence of frailty increased with age in both sexes; in the group aged 70-74 years, 1.8% of men and 3.7% of women were frail, whereas in the 80-84 years age group, 14.9% of men and 16.7% of women were frail. Women tended to exhibit a higher prevalence of frailty than men in all age groups. Future plans The KFACS plans to identify outcomes and risk factors associated with frailty by conducting a 10-year cohort study, with a follow-up every 2 years, using 3014 baseline participants.

KW - geriatric medicine

KW - preventive medicine

KW - public health

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DO - 10.1136/bmjopen-2019-035573

M3 - Article

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AN - SCOPUS:85084030439

SN - 2044-6055

VL - 10

JO - BMJ open

JF - BMJ open

IS - 4

M1 - e035573

ER -

Korean frailty and aging cohort study (KFACS): Cohort profile

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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