Abstract
Two new spiro-lanostane triterpenoids, antrolactones A and B (1 and 2), along with polyporenic acid C (3), were isolated from an EtOAc-soluble extract of Antrodia heteromorpha culture medium, and the chemical structures of the new compounds were elucidated by application of NMR, MS, and ECD spectroscopic techniques. All isolated compounds exhibited inhibitory effects on receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis.
Original language | English |
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Pages (from-to) | 1689-1693 |
Number of pages | 5 |
Journal | Journal of Natural Products |
Volume | 79 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2016 Jun 24 |
Bibliographical note
Funding Information:This research was supported by a grant from the National Research Foundation of Korea ( NRF-2015R1D1A1A01060321) and the KRIBB Research Initiative Program.
Publisher Copyright:
© 2016 The American Chemical Society and American Society of Pharmacognosy.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
ASJC Scopus subject areas
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry