Laser Microsurgery in Caenorhabditis elegans

Christopher Fang-Yen, Christopher V. Gabel, Aravinthan D.T. Samuel, Cornelia I. Bargmann, Leon Avery

Research output: Chapter in Book/Report/Conference proceedingChapter

90 Citations (Scopus)


Laser killing of cell nuclei has long been a powerful means of examining the roles of individual cells in C. elegans. Advances in genetics, laser technology, and imaging have further expanded the capabilities and usefulness of laser surgery. Here, we review the implementation and application of currently used methods for target edoptical disruption in C. elegans.

Original languageEnglish
Title of host publicationMethods in Cell Biology
PublisherAcademic Press Inc.
Number of pages30
Publication statusPublished - 2012

Publication series

NameMethods in Cell Biology
ISSN (Print)0091-679X

Bibliographical note

Funding Information:
We thank John Sulston and Ron Ellis for allowing us to include Figs. 2 and 4 and Fig. 3 , respectively, and Niels Ringstad for helpful comments. This work was supported by the National Science Foundation and National Institutes of Health.


  • Ablation
  • Chemosensation
  • Laser killing
  • Microbeam
  • Microfluidics
  • Microsurgery

ASJC Scopus subject areas

  • Cell Biology


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