Abstract
This paper presents a technique that can provide accurate hemoglobin concentration measurement within a simple, cost-effective and compact platform. It is based on a LED and CMOS image sensor without using an environmentally harmful reagent and centrifugal process. The acquired standard curve and adequate image processing steps such as image calibration and noise suppression allow us to accurately estimate the hemoglobin concentration at an error rate of less than 2% for blind tests conducted with the 33 blood specimens of outpatients. The hemoglobin concentration measurement, one of the crucial part of the complete blood count (CBC) as well as the most commonly ordered test in clinical laboratory, within such a small, cheap and fast platform would be useful for wide applications in doctor's office and for applications in resource limited settings as a point-of-care testing tool.
Original language | English |
---|---|
Pages (from-to) | 103-109 |
Number of pages | 7 |
Journal | Sensors and Actuators, B: Chemical |
Volume | 157 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2011 Sept 20 |
Keywords
- Blood analysis
- CMOS image sensor
- Hemoglobin concentration measurement
- LED
- Spectrophotometry
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Instrumentation
- Condensed Matter Physics
- Surfaces, Coatings and Films
- Metals and Alloys
- Electrical and Electronic Engineering
- Materials Chemistry