LED and CMOS image sensor based hemoglobin concentration measurement technique

Dong Sik Kim, Jae Hoon Choi, Myung Hyun Nam, Ji Woon Yang, James Jungho Pak, Sungkyu Seo

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


This paper presents a technique that can provide accurate hemoglobin concentration measurement within a simple, cost-effective and compact platform. It is based on a LED and CMOS image sensor without using an environmentally harmful reagent and centrifugal process. The acquired standard curve and adequate image processing steps such as image calibration and noise suppression allow us to accurately estimate the hemoglobin concentration at an error rate of less than 2% for blind tests conducted with the 33 blood specimens of outpatients. The hemoglobin concentration measurement, one of the crucial part of the complete blood count (CBC) as well as the most commonly ordered test in clinical laboratory, within such a small, cheap and fast platform would be useful for wide applications in doctor's office and for applications in resource limited settings as a point-of-care testing tool.

Original languageEnglish
Pages (from-to)103-109
Number of pages7
JournalSensors and Actuators, B: Chemical
Issue number1
Publication statusPublished - 2011 Sept 20

Bibliographical note

Funding Information:
This research was supported by the Converging Research Center Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (no. 20090083290 ).


  • Blood analysis
  • CMOS image sensor
  • Hemoglobin concentration measurement
  • LED
  • Spectrophotometry

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry


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