Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study

Dong Keun Seok; Sae Yoon Kee; Soon Young Ko; Jung Hwa Lee; Hye Young Kim; In Sun Kim; Hee Yeon Seo

doi:10.3892/ol.2013.1580

Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study

Dong Keun Seok, Sae Yoon Kee, Soon Young Ko, Jung Hwa Lee, Hye Young Kim, In Sun Kim, Hee Yeon Seo

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Abstract

Acute myeloid leukemia presenting as leukemia cutis (LC) with hepatocellular carcinoma is extremely rare. The current study presents a case of a 53-year-old male with generalized cutaneous nodules on the face and anterior chest wall. Laboratory tests, including bone marrow biopsy revealed acute myelomonocytic leukemia (AML-M4) with skin and tonsilar involvement. Liver magnetic resonance imaging (MRI) revealed a 6-cm mass in hepatic segments 4 and 8, and a liver biopsy demonstrated that hepatocellular carcinoma cells and immature blast cells coexisted. Although LC has been reported in Korea, a case of LC associated with acute myelomonocytic leukemia was diagnosed simultaneously with hepatocellular carcinoma and tonsillar involvement. The present study describes this case with a review of the literature.

Original language	English
Pages (from-to)	1319-1322
Number of pages	4
Journal	Oncology Letters
Volume	6
Issue number	5
DOIs	https://doi.org/10.3892/ol.2013.1580
Publication status	Published - 2013 Nov
Externally published	Yes

Keywords

Hematologic neoplasm
Solid neoplasm
Synchronous primary neoplasms

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3892/ol.2013.1580

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title = "Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study",

abstract = "Acute myeloid leukemia presenting as leukemia cutis (LC) with hepatocellular carcinoma is extremely rare. The current study presents a case of a 53-year-old male with generalized cutaneous nodules on the face and anterior chest wall. Laboratory tests, including bone marrow biopsy revealed acute myelomonocytic leukemia (AML-M4) with skin and tonsilar involvement. Liver magnetic resonance imaging (MRI) revealed a 6-cm mass in hepatic segments 4 and 8, and a liver biopsy demonstrated that hepatocellular carcinoma cells and immature blast cells coexisted. Although LC has been reported in Korea, a case of LC associated with acute myelomonocytic leukemia was diagnosed simultaneously with hepatocellular carcinoma and tonsillar involvement. The present study describes this case with a review of the literature.",

keywords = "Hematologic neoplasm, Solid neoplasm, Synchronous primary neoplasms",

author = "Seok, {Dong Keun} and Kee, {Sae Yoon} and Ko, {Soon Young} and Lee, {Jung Hwa} and Kim, {Hye Young} and Kim, {In Sun} and Seo, {Hee Yeon}",

year = "2013",

month = nov,

doi = "10.3892/ol.2013.1580",

language = "English",

volume = "6",

pages = "1319--1322",

journal = "Oncology Letters",

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publisher = "Spandidos Publications",

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TY - JOUR

T1 - Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma

T2 - A case study

AU - Seok, Dong Keun

AU - Kee, Sae Yoon

AU - Ko, Soon Young

AU - Lee, Jung Hwa

AU - Kim, Hye Young

AU - Kim, In Sun

AU - Seo, Hee Yeon

PY - 2013/11

Y1 - 2013/11

N2 - Acute myeloid leukemia presenting as leukemia cutis (LC) with hepatocellular carcinoma is extremely rare. The current study presents a case of a 53-year-old male with generalized cutaneous nodules on the face and anterior chest wall. Laboratory tests, including bone marrow biopsy revealed acute myelomonocytic leukemia (AML-M4) with skin and tonsilar involvement. Liver magnetic resonance imaging (MRI) revealed a 6-cm mass in hepatic segments 4 and 8, and a liver biopsy demonstrated that hepatocellular carcinoma cells and immature blast cells coexisted. Although LC has been reported in Korea, a case of LC associated with acute myelomonocytic leukemia was diagnosed simultaneously with hepatocellular carcinoma and tonsillar involvement. The present study describes this case with a review of the literature.

AB - Acute myeloid leukemia presenting as leukemia cutis (LC) with hepatocellular carcinoma is extremely rare. The current study presents a case of a 53-year-old male with generalized cutaneous nodules on the face and anterior chest wall. Laboratory tests, including bone marrow biopsy revealed acute myelomonocytic leukemia (AML-M4) with skin and tonsilar involvement. Liver magnetic resonance imaging (MRI) revealed a 6-cm mass in hepatic segments 4 and 8, and a liver biopsy demonstrated that hepatocellular carcinoma cells and immature blast cells coexisted. Although LC has been reported in Korea, a case of LC associated with acute myelomonocytic leukemia was diagnosed simultaneously with hepatocellular carcinoma and tonsillar involvement. The present study describes this case with a review of the literature.

KW - Hematologic neoplasm

KW - Solid neoplasm

KW - Synchronous primary neoplasms

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U2 - 10.3892/ol.2013.1580

DO - 10.3892/ol.2013.1580

M3 - Article

AN - SCOPUS:84884471934

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SP - 1319

EP - 1322

JO - Oncology Letters

JF - Oncology Letters

IS - 5

ER -

Leukemia cutis in a patient with acute monocytic leukemia diagnosed simultaneously with hepatocellular carcinoma: A case study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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