Lithium-halogen exchange reaction using microreaction technology

Jaehoon Choe, Jung Hyun Seo, Youngwoon Kwon, Kwang Ho Song

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


A two-stage continuous microreactor system was use to synthesize the materials for an organic light emitting diode. The split and recombine type of micromixers were suitable for the two-stage reaction including lithium-bromo exchange reaction. The two-stage synthesis was carried out under non-cryogenic conditions by taking full advantage of microstructured reaction systems. In a first stage, the unstable intermediate, naphthyl lithium was synthesized with maximum yield and consumed immediately in the second stage micromixer. The naphthyl-substituted anthracene was obtained with 97% purity.

Original languageEnglish
Pages (from-to)S17-S20
JournalChemical Engineering Journal
Issue numberSUPPL. 1
Publication statusPublished - 2008 Jan 15

Bibliographical note

Funding Information:
This work has been supported by the Next Generation Novel Technology Development Program of the Ministry of Commerce, Industry and Energy (MOCIE) under the project title of “Development of Micro-Optical and Thermofluidic Devices with High Functionality.”


  • Bromonaphthalene
  • Electron transport layer
  • Microreaction technology

ASJC Scopus subject areas

  • General Chemistry
  • Environmental Chemistry
  • General Chemical Engineering
  • Industrial and Manufacturing Engineering


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